Publications by authors named "S A Bessonova"

Aim: To present single-center experience and results of surgical treatment of acquired tracheal stenosis.

Material And Methods: There were 99 patients with acquired tracheal stenosis for the period from January 2008 to December 2017. Median age was 39 (28; 55) years (range 19-79 years), male/female ratio - 64/35.

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Article Synopsis
  • Channel-mediated chloride movement is crucial for regulating cell volume during osmotic stress, but thymocytes may use a K-Cl cotransport mechanism instead.
  • Two types of anion conductance were activated by osmotic swelling, identified as a maxi-anion channel and a volume-sensitive outwardly rectifying (VSOR) chloride channel.
  • Phloretin significantly inhibited VSOR-type conductance, while DIOA strongly suppressed VSOR single-channel activity, suggesting both channels play important roles in cellular response to hypotonic conditions.
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Apoptosis is a distinct form of cell death, which requires energy. Here, we made real-time continuous measurements of the cytosolic ATP level throughout the apoptotic process in intact HeLa, PC12 and U937 cells transfected with the firefly luciferase gene. Apoptotic stimuli (staurosporine (STS), tumor necrosis factor alpha (TNFalpha), etoposide) induced significant elevation of the cytosolic ATP level.

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In tests conducted with 65 male-rats of the Wistar line, aged 2-3 months subject to studies was the effect of retabolil (RB) and thyrocalcitonine (TCT) on the mineral metabolism in the osseous tissue following fracture of the lower jaw. The per cent of the Ca45 isotope incorporation in the injured and unaffected (contralateral) sections of the jaw and also in the thigh bones, lying far away from the site of the injury, was determined in dynamics. The agents RB and TCT, displaying different modes of action, produce a similarly oriented effect, viz.

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