[Changes in the lymph nodes of adrenalectomized rats with staphylococcal poisoning].

Histological changes in lymph nodes and dynamics of 11-oxycorticosteroid levels in blood were studied in intact and adrenalectomized rats under staphylococcal intoxication. At early stages (up to 24 h) after staphylotoxin or staphylococcal injection, stress reaction of the organism, which produces a rise of corticosteroid level in blood, was demonstrated to play the major role in aplasy of the lymphoid tissue. At later stages, when the level of corticosteroids decreases, the lymphoid tissue begins to restore.

[Bactericidal effect of cationic proteins of cellular origin on staphylococci].

A study was made of the bactericidal action of thymus histones, histone-like substance, from the nuclei of rabbit leukocytes and lysosomal cation proteins from the same leukocyte on different staphylococcus cultures. The majority of the strains of coagulasoneagative staphylococci perished under the effect of the preparations tested; cultures forming this enzyme retained their viability, irrespective of their virulence for mice, their capacity to the lecithinase formation and to mannite fermentation. The preparations studied possessed a different bactericidal activity.