Publications by authors named "S A Alissa"

Ganglion cysts are typically periarticular soft tissue lesions commonly found in the wrist and forearm, with spinal involvement being rare. We present a clinical case of a 54-year-old female with a ganglion cyst at the L3-L4 level, causing radiculopathy symptoms. Despite initial difficulty in diagnosis due to MRI findings, surgical resection confirmed the extradural mass as a ganglion cyst.

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Beckwith-Wiedemann syndrome (BWS) is a complex congenital overgrowth disorder necessitating a multidisciplinary approach for effective management. A 5-year-old Saudi girl with BWS received comprehensive care involving various specialists, including a plastic surgeon who performed a keyhole technique tongue reduction to address macroglossia. The intervention resulted in significant improvements in speech and quality of life, with no postoperative complications.

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The role of vision in maintaining postural stability is crucial, and its loss, whether congenital or acquired, can significantly impact sensory-motor interactions, leading to musculoskeletal abnormalities and defective gait patterns. This case report discusses the complex interplay between visual impairment, post-traumatic kyphosis, and the development of spinal deformity in a 79-year-old blind patient. The patient sustained a simple fall resulting in an L1 compression fracture in 2016.

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Alkaptonuria is a rare genetic disorder characterized by the excessive production of homogentisic acid, leading to the formation and deposition of pigment polymers throughout the body. It is extremely rare, affecting only around one in 100,000 individuals. Despite the normal life expectancy, it can cause severe morbidities.

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Article Synopsis
  • Lipoatrophy and lipodystrophy are often confused but have key differences, particularly regarding the role of inflammation in subcutaneous adipose tissue (SAT) loss; lipoatrophy involves inflammation while lipodystrophy does not.
  • SAT loss can occur due to both acquired causes (like drug injections or injuries) and congenital causes (like familial partial lipodystrophy and congenital generalized lipodystrophy), each with varying mutations and clinical signs.
  • A case study highlighted a 12-year-old girl with SAT loss in her left lower limb since birth, lacking inflammation, leading to a suspected diagnosis of familial partial lipodystrophy; genetic testing was inconclusive, and she will undergo conservative therapy
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