[Surgical treatment of spontaneous pneumothorax].

Results of treatment of 230 patients with the spontaneous pneumothorax were analyzed. All patients were divided in 4 groups, depending on the method of treatment. 1 group consisted of 2 patients, who were successfully treated, using pleural puncture.

[Preventive surgical treatment of ulcer disease].

The state of gastric secretion in ulcer disease patients was investigated. Acidity was estimated by a computed analysis of 24 hour acidogastromonitoring with apparatus AG-24 MP "Gastroscan-24". The examination of 739 patients with chronic duodenal ulcers included 139 (18.

[Strategy of surgical treatment of ulcer disease].

Results of treatment of 688 patients who have undergone palliative operations for complicated forms of gastric and duodenal ulcer, and 2,269 patients after radical surgery were analyzed. It is demonstrated that pharmacotherapy is ineffective in 9% patients with uncomplicated ulcer, in 32% patients with previous ulcer bleeding, and in 29% patients after suturing of perforated ulcer. The role of preventive operation is demonstrated: postoperative complications in this group are revealed rarely compared with those operated for complicated forms of the disease.

[Clinical and economic assessment of treatment efficacy of uncomplicated duodenal ulcer with different antisecretory agents in hospital].

A study of 197 patients with uncomplicated duodenal ulcer revealed clinical and pH-metric particular features of the action of pariet (rabeprazole) and six secretolytics: cimetidine, ranitidine, ranisan, quamatel, omez. It was established that the main clinical criteria of treatment efficacy is duration of ulcer cicatrisation and percentage of cicatrized ulcers during 21 days, and additional criteria are duration of disappearance of clinical signs and stage of acid production suppression. Possibilities of applying methods of pharmacoeconomic study were examined: analysis of the treatment cost, cost minimization, and cost-efficacy with the definition of the increase of expense efficacy for drug selection.

[Rehabilitation of patients after suturing perforated duodenal ulcer].

516 patients with perforated duodenal ulcer were operated, 396 of them underwent palliative operations. Long-term results were studied in 237 patients. Determination of individual sensitivity to H2-blockers of histamine receptors with 24 hour pH-metry demonstrated tendency towards reduction of therapeutic effect time, and in 17-18% cases--resistance development.