Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS).

The purpose of the study was to evaluate the efficacy and safety of vitamin D3 at 4000 IU/day as a treatment option for aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) when compared with the usual care dose of 600 IU D3. We conducted a single site randomized, double-blind, phase 3 clinical trial in women with AIMSS comparing change in symptoms, reproductive hormones and AI pharmacokinetics. Postmenopausal women ≥18 years with stages I-IIIA breast cancer, taking AI and experiencing AIMSS [breast cancer prevention trial symptom scale-musculoskeletal (BCPT-MS) subscale ≥1.

A randomized controlled trial comparing a low-residue diet versus clear liquids for colonoscopy preparation: impact on tolerance, procedure time, and adenoma detection rate.

Objective: To achieve an excellent bowel preparation, it is routine to require a clear liquid diet on the day before the procedure. Unfortunately, this dietary modification may be poorly tolerated. We examine whether a change in precolonoscopy dietary restriction can lead to better patient tolerance without compromising examination quality.

A self-report instrument measuring readiness to change disordered eating behaviors: the Eating Disorders Stage of Change.

Objective: To evaluate the utility of the Eating Disorders Stage of Change (EDSOC), a behavior-specific readiness questionnaire.

Method: Patients (N=145) at a multidisciplinary eating disorder treatment facility in the United States completed the EDSOC and other questionnaires.

Results: One-week test-retest reliability was strong across eating disorder diagnoses and age groups.

When ''no'' means ''yes'': the gender implications of HIV programming in a Zimbabwean university.

Objectives: This study assessed the nature and extent of sexual risk-taking behavior by students in a Zimbabwean university and identified some of the sociocultural factors that facilitate sexual risk taking by female and male students. The main outcome measures of the study were condom use, number of sexual partners, and attitudes toward gender equity and equality.

Methods: A cross-sectional design was used and a questionnaire was administered to 933 students.