Improving sensitivity of XANES structural fit to the bridged metal-metal coordination.

Hard X-ray absorption spectroscopy is a valuable in situ probe for non-destructive diagnostics of metal sites. The low-energy interval of a spectrum (XANES) contains information about the metal oxidation state, ligand type, symmetry and distances in the first coordination shell but shows almost no dependency on the bridged metal-metal bond length. The higher-energy interval (EXAFS), on the contrary, is more sensitive to the coordination numbers and can decouple the contribution from distances in different coordination shells.

Spectral studies of soft x-ray radiation of laser-produced plasma of various target materials in a wide spectral range.

The work is devoted to experimental study of soft x-ray radiation spectra of laser-produced plasma in a wide spectral range of 5-100Å at the Kamerton facility (GPI) with pulse duration 70 ps, pulse energy 1-5J, and wavelength 0.53 microns at which the laser intensity (power flux density) of 7×10^{14}-3.5×10^{15}W/cm^{2} was achieved.

[Morphometric and immunohistochemical markers of breast cancer progression].

The results of the study for the last decade aimed at the search of markers of mammary carcinoma malignancy and prognosis are reported. Accumulation and integration of various data contributes not only to more precise identification of the malignancy but also to more complete understanding of biological essence of mammary carcinoma.

[The role of cell communication in the pathogenesis of breast cancer].

A complex histochemical, morphometric and immunohistochemical study of communication systems, i.e. histophysiological clusters of vegetative nervous terminals, the microcirculatory bed and their immediate cellular microenvironments has been conducted.

[Morphogenetic potential of the communication systems in breast dysplasia and fibroadenoma].

The results of this study indicate participation of the adrenergic vegetative neural terminals (VNT) in the stroma formation due to indirect influence on the vascular structures. The involvement of the immunocompetent cells in these processes is not denied. Moreover, the determining role of VNT of the adrenergic part in the development of dysplasia can be suggested.