Molluscicidal assessment of certain toxicants: Impact on biochemical alterations and electrophoretic protein patterns in Massylaea vermiculata (O. F. Müller, 1774) snails.

Massylaea vermiculata snails are a significant gastropod pest in Egypt, threatening agriculture. Due to increasing concerns about conventional pesticides, it is imperative to find effective alternatives that are less harmful. We assessed the molluscicidal activity of abamectin, methoxyfenozide, and spinosad using the leaf-dipping method in vitro and the effect of LC of these compounds on biochemical aspects and protein electrophoresis.

Enhancing the anticancer potential of metformin: fabrication of efficient nanospanlastics, cytotoxic studies on HEP-2 cells and reactome enhanced pathway analysis.

Metformin (MET), an oral antidiabetic drug, was reported to possess promising anticancer effects. We hypothesized that MET encapsulation in unique nanospanlastics would enhance its anticancer potential against HEP-2 cells. Our results showed the successful fabrication of Nano-MET spanlastics (d = 232.