Direct selenosulfonylation of unsaturated compounds: a review.

In this review, we have discussed recent developments on the direct selenosulfonylation of unsaturated compounds which lead to the formation of two new carbon-sulfur and carbon-selenium bonds in a single operation. The reactions were classified based on the type of starting unsaturated compound and product. Thus, the review is divided into three major sections.

The recent development of donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's agents: highlights from 2010 to 2020.

Dementia is a term used to define different brain disorders that affect memory, thinking, behavior, and emotion. Alzheimer's disease (AD) is the second cause of dementia that is generated by the death of cholinergic neurons (especially acetylcholine (ACh)), which have a vital role in cognition. Acetylcholinesterase inhibitors (AChEI) affect acetylcholine levels in the brain and are broadly used to treat Alzheimer's.

Vicinal halo-trifluoromethylation of alkenes.

Both trifluoromethyl and halide groups are widely found in medicinally and pharmaceutically important compounds and, moreover, organohalides are commonly used as versatile intermediates in synthetic organic chemistry. Due to their prevalence and easy accessibility, alkene halo-trifluoromethylation provides a convenient way to install these valuable functionalities in complex targets. In this review, we summarize recent advances and achievements in this fast-growing research field.

Characterization of titanium influences on structure and thermodynamic stability of novel CTi nanofullerenes (n=1-5): a density functional perspective.

In this survey, effects of titanium heteroatom(s) on structural parameters and thermodynamic stability of C fullerene and its CTi derivatives (n = 1-5) are compared and contrasted, at DFT levels of theory. The results show that in going from CTi to CTi, binding energy increases while absolute value heat of atomization decreases. According to vibrational frequency analysis, excepting CTi, the other optimized structures give no imaginary frequency as true minima.