Development and validation of claims-based algorithms to identify pregnancy based on data from a university hospital in Japan.

Objective: When using administrative data, validation is essential since these data are not collected for research purposes and misclassification can occur. Thus, this study aimed to develop algorithms identifying pregnancy and to evaluate the validity of administrative claims data in Japan.

Methods: All females who visited the Tohoku University Hospital Department of Obstetrics in 2018 were included.

Association of home and office systolic and diastolic hypertension with glucose metabolism in a general population: the Ohasama study.

Objective: This study was performed to investigate the association of hypertension subtypes with glucose metabolism among the Japanese general population.

Methods: The study involved 646 residents (mean age: 62.4 years) without treatment for hypertension or a history of diabetes from Ohasama, a rural Japanese community, who underwent an oral glucose tolerance test.

Coverage of Clinical Research Data Retrieved from Standardized Structured Medical Information eXchange Storage.

Clinical researchers hold high expectations for the utility of health data sourced from hospital information systems. In Japan, the standardized structured medical information eXchange version 2 (SS-MIX2) storage is a common resource for obtaining clinical data from different medical databases. However, little is known about the coverage of the data types derived from the SS-MIX2 storage.

Electronic Phenotyping to Identify Patients with Arrythmia Disease from a Hospital Information System.

Electronic phenotyping is an important method to identify a disease group by collecting clinical data from hospital information systems. This study aimed to extract accurate cases of supraventricular arrythmia, ventricular arrythmia, and bradycardia from clinical data of a hospital information system. The electronic phenotyping algorithm was improved using the machine learning method.

Validity of Administrative Data for Identifying Birth-Related Outcomes with the End Date of Pregnancy in a Japanese University Hospital.

This study aimed to develop and validate claims-based algorithms for identifying live birth, fetal death, and cesarean section by utilizing administrative data from a university hospital in Japan. We included women who visited the Department of Obstetrics at a university hospital in 2018. The diagnosis, medical procedures, and medication data were used to identify potential cases of live birth, fetal death, and cesarean section.

Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study.

Objective: We aimed to explore the association between regular dental visits and atherosclerosis and between periodontitis, number of remaining teeth, and atherosclerosis among community dwellers in Japan.

Background: Few studies have examined the association between regular dental visits, periodontitis, tooth loss, and atherosclerosis in community dwellers in Japan.

Methods: The participants of this cross-sectional study included community dwellers aged ≥55 years and residing in Ohasama.

Validity of identification algorithms combining diagnostic codes with other measures for acute ischemic stroke in MID-NET®.

Purpose: We aimed to develop a reliable identification algorithm combining diagnostic codes with several treatment factors for inpatients with acute ischemic stroke (AIS) to conduct pharmacoepidemiological studies using the administrative database MID-NET® in Japan.

Methods: We validated 11 identification algorithms based on 56 different diagnostic codes (International Classification of Diseases, Tenth Revision; ICD-10) using Diagnosis Procedure Combination (DPC) data combined with information on AIS therapeutic procedures added as "AND" condition or "OR" condition. The target population for this study was 366 randomly selected hospitalized patients with possible cases of AIS, defined as relevant ICD-10 codes and diagnostic imaging and prescription or surgical procedure, in three institutions between April 1, 2015 and March 31, 2017.

Association between urinary sodium-to-potassium ratio and home blood pressure and ambulatory blood pressure: the Ohasama study.

Objective: No studies have demonstrated the association between urinary sodium-to-potassium (Na/K) ratio and all out-of-office blood pressure (BP) [home morning and evening BP (self-measured at home), and 24-h, daytime, and night-time ambulatory BP] in the same cohort. We aimed to assess, which type of out-of-office BP is more strongly associated with urinary Na/K ratio in the general population.

Methods: This cross-sectional study was conducted in the general population of Ohasama, Japan.

Prediction Models for the 5- and 10-Year Incidence of Home Morning Hypertension: The Ohasama Study.

Background: We aimed to develop risk prediction models for new-onset home morning hypertension.

Methods: We followed up 978 participants without home hypertension in the general population of Ohasama, Japan (men: 30.1%, age: 53.

Health Information Exchange between Specialists and General Practitioners Benefits Rural Patients.

Background: Health information exchange (HIE) may improve diagnostic accuracy, treatment efficacy, and safety by providing treating physicians with expert advice. However, most previous studies on HIE have been observational in nature.

Objectives: To examine whether collaboration between specialists and general practitioners (GPs) in rural areas via HIE can improve outcomes among patients at low-to-moderate risk of cardiovascular disease, kidney disease, and stroke.

Electronic Phenotyping to Identify Patients with Heart Failure Using a National Clinical Information Database in Japan.

Unlabelled: Heart failure (HF) is a grave problem in the clinical and public health sectors. The aim of this study is to develop a phenotyping algorithm to identify patients with HF by using the medical information database network (MID-NET) in Japan.

Methods: From April 1 to December 31, 2013, clinical data of patients with HF were obtained from MID-NET.

Oral health-related quality of life is associated with the prevalence and development of depressive symptoms in older Japanese individuals: The Ohasama Study.

Objective: This prospective study investigated the cross-sectional association between impaired oral health-related quality of life (OHRQoL) and the prevalence of depressive symptoms, and the longitudinal association between impaired OHRQoL and development of depressive symptoms among older adults.

Background: Previous studies have shown a relationship between poor oral health and depression among older adults; however, findings are inconsistent.

Materials And Methods: Participants were 669 community-dwelling older Japanese individuals aged≥55 years (mean: 67.

Lifetime risk of stroke stratified by chronic kidney disease and hypertension in the general Asian population: the Ohasama study.

Lifetime risk (LTR) evaluates the absolute risk of developing a disease during the remainder of one's life. It can be a useful tool, enabling the general public to easily understand their risk of stroke. No study has been performed to determine the LTR of cardiovascular disease in patients with chronic kidney disease (CKD) with or without hypertension; therefore, we performed this study in an Asian population.

Blood Pressure Phenotypes Defined by Ambulatory Blood Pressure Monitoring and Carotid Artery Changes in Community-Dwelling Older Japanese Adults: The Ohasama Study.

White coat hypertension is defined as elevated blood pressure in the office, but a normal blood pressure out-of-office, whereas masked hypertension is defined as elevated blood pressure in the office, but normal out-of-office blood pressure. The objective was to investigate the associations between these blood pressure phenotypes and carotid artery changes. Conventional blood pressure, ambulatory blood pressure, and carotid ultrasonography were evaluated in 851 Ohasama residents (31.

N-Terminal Pro-B-Type Natriuretic Peptide Is a Predictor of Chronic Kidney Disease in an Asian General Population - The Ohasama Study.

N-terminal pro-B-type natriuretic peptide (NT-proBNP) is known to increase in heart failure patients. Given that no reports have described the association between NT-proBNP and chronic kidney disease (CKD) incidence in Asian populations, we investigated this association in the Japanese population. We followed up 867 participants without CKD from the general population of Ohasama, Japan.

Age-Related Trends in Home Blood Pressure, Home Pulse Rate, and Day-to-Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study.

Background Home blood pressure is a more accurate prognosticator than office blood pressure and allows the observation of day-to-day blood pressure variability. Information on blood pressure change during the life course links the prediction of blood pressure elevation with age. We prospectively assessed age-related trends in home blood pressure, home pulse rate, and their day-to-day variability evaluated as a coefficient of variation.

Development and evaluation of a home nocturnal blood pressure monitoring system using a wrist-cuff device.

Objective: The conventional nocturnal blood pressure monitoring (NBPM) systems can disturb sleep and lead to false measurements. The present study compared the validity and acceptability of a newly developed wrist-cuff system with that of the conventional upper arm-cuff system for NBPM.

Participants And Methods: Home blood pressure (BP) and pulse rate (PR) were measured in hypertensive patients (n=57) every 30 min at night using a wrist-cuff system and at 2 am (fixed time) and 4 h after going to bed (flexible time) using an upper arm-cuff system.

Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study.

Background: Numerous prospective studies have investigated the association between the number of remaining teeth and dementia or cognitive decline. However, no agreement has emerged on the association between tooth loss and cognitive impairment, possibly due to past studies differing in target groups and methodologies. We aimed to investigate the association between tooth loss, as evaluated through clinical oral examinations, and the development of cognitive impairment in community-dwelling older adults while considering baseline cognitive function.

N-Terminal Pro-B-Type Natriuretic Peptide Is Not a Significant Predictor of Stroke Incidence After 5 Years - The Ohasama Study.

Background: N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been used for risk stratification in heart failure or acute coronary syndrome, but the beyond 5-year predictive value of NT-proBNP for stroke remains an unsettled issue in Asian patients. The aim of the present study was to clarify this point.

Methods and results: We followed 1,198 participants (33.

Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study.

We compared the predictive power for a major adverse cardiovascular event (MACE) of four home blood pressure (BP) indices (systolic BP, diastolic BP, mean BP, and pulse pressure (PP)) obtained at baseline before treatment and during the on-treatment follow-up period in 3147 patients with essential hypertension (women: 50.1%, mean age: 59.5 years).

Development of algorithms to determine the onset of pregnancy and delivery date using health care administrative data in a university hospital in Japan.

Purpose: To develop and assess algorithms to determine the onset of pregnancy and delivery date using health administrative data from a university hospital in Japan.

Methods: All women who were hospitalized in the maternity ward and had at least one pregnancy that ended with a delivery during the period of January 2014 and December 2015 were included in this study. The true delivery date was obtained from the electronic medical records and was used as a gold standard.