[A Case of Recurrent Gallbladder Cancer with a Complete Response to S-1 Alternate-Day Administration].

An 86-year-old woman underwent a cholecystectomy for gallbladder cancer. Seven months later, an abdominal CT scan showed multiple liver and lymph node metastases. Treatment with S-1 was started at a dose of 100 mg/day, but was changed to alternate-day administration because of diarrhea.

UDP-glucuronosyltransferase (UGT) 1A1*28 polymorphism-directed phase II study of irinotecan with 5'-deoxy-5-fluorouridine (5'-DFUR) for metastatic colorectal cancer.

Aim: We performed a phase II study of irinotecan with 5'-deoxy-5-fluorouridine (5'-DFUR) for metastatic colorectal cancer based on UDP-glucuronosyltransferase (UGT) 1A1 polymorphism.

Patients And Methods: A total of 28 patients were enrolled. The dose of irinotecan was 150 mg/m(2) for patients with the *1/*1 wild-type genotype, and 70 mg/m(2) for those with the *1/*28 mutated genotype.

Effects of hemofiltration on liver regeneration after hepatectomy.

Background/aims: In modern medicine, blood purification methods are used for a variety of diseases and applications in the field of hepatic disorders. The purpose of this study was to clarify the effects of blood purification on liver regeneration just after hepatectomy.

Methodology: Beagle dogs received 70% hepatectomy and were divided into two groups according to the use (hemofiltration group) or absence (controls) of hemofiltration just after surgery.

[A case report of 4-year survival of the patient with transverse colon cancer with multiple liver and lymph node metastases--multidisciplinary approach].

A 47-year-old male presented to our Hospital in February 2005 with acute colonic obstruction due to transverse colon cancer. The patient had undergone emergency transverse colectomy with loop colostomy. After stabilization of patient's general condition, a further investigation revealed multiple liver metastases.