[Prevalence of Risk Factors of Non-Communicable Disease in Kyrgyzstan: Assessment using WHO STEPS Approach].

Assessment of prevalence of risk factors for non-communicable diseases (NCD) based on WHO "STEPS" approach was conducted in Kyrgyzstan. Results of this study demonstrated high prevalence of NCD risk factors: 94.2% of subjects aged 24-64 years had risk factors.

[Effect of ionizing radiation on the lipid fatty acid composition of the plasma membranes of liver cells].

Changes in the fatty acid composition of total lipids and individual phospholipids of liver cell plasma membranes of intact and exposed (7.65 Gy) rats have been studied. The authors discuss the relationship between the degree of lipid oxidation and other lipid characteristics of the studied membrane after exposure to ionizing radiation.

[Antioxidative activity of plasma membrane lipids of liver cells and its change after irradiation].

Antioxidative activity (AOA) of lipids was revealed in plasma membranes of rat liver cells. The dynamics of its change after total-body X- irradiation with a dose 7.65 Gy was followed up.

[The effect of irradiation on the lipid composition of plasma membranes of liver cells].

The level of total phospholipids decreases, a cholesterol/phospholipid molar coefficient increases, and lipid/protein ratio in plasma membranes of liver cells decreases at early times following total-body X-irradiation of rats (LD50/30). Changes in individual phospholipids were differently directed. A possible correlation between the data obtained and the structural-functional status of the surface membrane is discussed.

[Radiation effects in plasma membranes based on infrared spectroscopy].

A study was made of the infra-red spectra of rat liver plasma membranes at different times after X-irradiation. Changes in the polypeptide chain mobility and protein conformation, an increase in hydrophobic interactions of fatty acid residues of phospholipids, and inhibition of auto- and induced oxidation of lipids were detected.

[Antiradical protective systems in the plasma membranes of an irradiated animal].

In the purified plasma membranes of rat liver the antiradical protection systems were revealed involving superoxide dismutase, glutathione peroxidase, glutathione reductase, lipid-dependent and water-soluble catalase, and reduced glutathione. Early changes were observed in these systems after total-body X-irradiation (LD50/30). The authors discuss the role of a plasma membrane in the radiation response of cells.

[Effect of adrenaline on the ATPase activity of rat liver plasma membranes].

In vivo and in vitro adrenaline affected dissimilarly the activity of Na+, K+-, HCO3- and Mg2+-ATPases from plasmatic membranes of rat liver tissue. Inhibition of Na+, K+-ATPase and stimulation of Mg2+-ATPase activities were observed within 1, 24 and 48 hrs after subcutaneous administration of the hormone at a dose of 0.3 and 1.

[Bicarbonate-stimulated ATP-ase from membranes of rat erythrocytes].

A bicarbonate-stimulating effect on the ATPase activity in membranes of rat erythrocytes depended upon pH, concentration of Mg2+ and HCO3-ions. Sodium azide and sodium thiocyanate distinctly inhibited the ATPase activity; pentachlorphenol and 2,4-dinitrophenol did not change it. Properties of the bicarbonate-stimulated ATPase from erythrocyte membranes were shown to be similar to the properties of the HCO3--ATPases from other cells.

[HCO3-sensitive adenosinetriphosphatase from ascites tumour cells].

HCO3--sensitive ATPase was found in nuclear and plasma membrane fractions of Ehrlich ascites tumour cells and lymphoma NK cells. HCO3--ATPase was not sensitive to monovalent cations and to ouabain (10(-4) M). The 60 mM HCO3- is the concentration of maximal activation of the HCO3--sensitive ATPase.