The metabolism of the norisoprenoid -ionone was investigated using human liver microsomes and 11 different recombinant cytochrome P450 enzymes expressed in cells. -Ionone was found to be oxidized via 4-hydroxylation by CYP2B6 in human liver microsomes. CYP1A2 also regioselectively catalyzed the hydroxylation of -ionone to yield 4-hydroxylation; this conversion was not stereoselective.
View Article and Find Full Text PDFThe chemical compositions of essential oils from the flower and aerial parts (i.e., leaf and branch) of Eurya japonica were determined and quantified using gas chromatography-mass spectrometry (GC-MS).
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