Publications by authors named "Ryoya Sekio"
Article Synopsis
- Habu snakes, a type of pit viper found in southwestern Japan, show physiological differences between populations on the islands of Tokunoshima and Amami-Oshima due to varying environmental factors.
- Research focused on the aortas of these snakes revealed that Tokunoshima Habu exhibited stronger contractile responses to certain substances like angiotensin II and acetylcholine compared to those from Amami-Oshima.
- The study found that acetylcholine caused contractions in the aortas of both populations, a discovery that had not been previously reported in snakes, suggesting significant differences in how these snakes react to vasoconstrictors.
Article Synopsis
- The study investigates vasoreactivity in the Tokara habu, a semi-arboreal snake native to two Japanese islands, expanding on previous research that focused mainly on terrestrial snakes.
- The researchers tested various vasoactive substances on isolated thoracic aortas and found that noradrenaline and angiotensin II caused contractions, while acetylcholine and serotonin induced a relaxation followed by contraction.
- This research indicates that the vasoreactive responses in semi-arboreal snakes may be more complex and involve different regulatory mechanisms compared to the more uniform responses seen in terrestrial snake species.*
The basilar arterial endothelium mediates blood vessel relaxation partly through the release of nitric oxide (NO). Apoptosis of cerebrovascular endothelial cells is linked to a high mortality rate in chickens infected with the highly pathogenic avian influenza virus, but interestingly, ducks exhibit a greater resistance to this virus. In this study, we examined the responsiveness of duck basilar arteries (BAs) to various vasoactive substances, including 5-hydroxytryptamine (5-HT), histamine (His), angiotensin (Ang) II, noradrenaline (NA), acetylcholine (ACh), and avian bradykinin ornithokinin (OK), aiming to characterize the receptor subtypes involved and the role of endothelial NO in vitro.
View Article and Find Full Text PDFThe response of basilar arteries to noradrenaline varies among many animal species, but remains little studied in poultry. Accordingly, we aimed to characterize the adrenergic receptor (AR) subtypes that modulate vascular response in basilar arteries in the chicken, with isometric recording of arterial ring tension using an organ bath. We demonstrated the presence of both alpha and beta (α and β) receptor subtypes through evaluating the response to noradrenaline, with and without a range of β-AR and α-AR antagonists.
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