Neoadjuvant imatinib may prevent tumor rupture and the need for extended surgery by reducing the tumor size by approximately 35%, especially for large gastric gastrointestinal stromal tumors(GISTs), as shown in a previous phase Ⅱ study (Kurokawa et al. BJC 2017); however, the use ofneoadjuvant imatinib is not prevalent in clinical practice. Herein, we report a large gastric GIST that was successfully treated with neoadjuvant imatinib.
View Article and Find Full Text PDFPrimary gastric undifferentiated pleomorphic sarcoma (UPS) is a rare disease with insufficient long-term follow-up data. In the present study, a 70-year-old male complained of abdominal fullness and visited our hospital. Abdominal computed tomography revealed a large tumor in the upper part of the stomach, which was accompanied by smaller tumors in the small intestinal mesentery.
View Article and Find Full Text PDFMesh migration is a rare complication of surgery for a hiatal hernia. Here, we present the case of a 72-year-old who complained of dysphasia and bodyweight loss. Upper gastrointestinal endoscopy revealed incarcerated mesh in the lumen of the esophagogastric junction.
View Article and Find Full Text PDFAim: The aim of this study was to clarify the clinical outcomes of staging laparoscopy(SL)for patients with positive peritonealwashing cytology(CY1P0)after S-1 administration.
Patients And Methods: Since 2007, eight CY1P0 patients who underwent SL after S-1 administration were enrolled. S-1 was administered according to the ACTS-GC and SL was performed after 8 courses of S-1 treatment.
A 64-year-old man with advanced gastric cancer presented with chief complaints of chest pain. His preoperative blood examination revealed positive results for serum HIV-antibody. His HIV-RNA level was 1.
View Article and Find Full Text PDFA 72-year-old Japanese man had a history of proximal gastrectomy for early gastric cancer located in the upper third of the stomach in 2007. Our usual treatment strategy for early gastric cancer in the upper third of the stomach in 2007 was open proximal gastrectomy reconstructing by jejunal interposition with a 10 cm single loop. Upper gastrointestinal fiberscopy for annual follow-up revealed a type 0-IIc-shaped tumor with ulcer scar, 4.
View Article and Find Full Text PDFWe herein present a case in which we used a totally laparoscopic approach for early gastric cancer accompanied by a huge hiatal hernia. An 80-year-old Japanese woman was referred with a chief complaint of dysphagia. A clinical diagnosis of early gastric cancer, T1b (SM) N0M0, stage IA, accompanied by hiatal hernia, was made.
View Article and Find Full Text PDFA 61-year-old woman was referred to our hospital with the complaint of severe dysphagia. Upper gastrointestinal endoscopy revealed an elevated tumor with an irregular surface located in the upper third of the stomach, and malignant melanoma was confirmed by biopsy specimens. Abdominal CT scan findings revealed that the tumor was invading the lateral segment of the liver and crus of the diaphragm.
View Article and Find Full Text PDFWe report here the effectiveness of chemoradiotherapy for a patient with local recurrence followed by curable gastrectomy. A 57-year-old man presented with a history of total gastrectomy with distal pancreatectomy and splenectomy, D2 lymphadenectomy, and Roux-en-Y reconstruction for advanced gastric cancer arising from the cardia. Esophageal intramural metastasis and lymph node metastasis around the right recurrent nerve were detected by chest-abdominal computed tomography and gastrointestinal endoscopy 27 months after the initial gastrectomy.
View Article and Find Full Text PDFWe report a case of complete response (CR) following induction chemotherapy using S-1 for a patient with early gastric cancer accompanied by multiple synchronous bone metastases. An asymptomatic 70-year-old woman was diagnosed with early gastric cancer by upper gastrointestinal endoscopy during a periodic medical examination. An abdomino-pelvic computed tomography (CT) scan revealed no primary tumor in the stomach and the absence of lymph node or liver metastases.
View Article and Find Full Text PDFSurgery is the most optimal and curative intent strategy for liver recurrence from colorectal cancer. There are scoring systems and grade classification for liver resection. If we carry out preoperative imaging of liver metastases strictly following to liver resection, we can expect to get a cure state satisfactory.
View Article and Find Full Text PDFA 52-year-old man who was diagnosed with esophagogastric junction cancer underwent left thoracolaparotomy and total gastrectomy. At 3 years and 11 months after the surgery, his carcinoembryonic antigen value was elevated, and cervical and right paraesophageal lymph node enlargement was detected by chest computed tomography(CT). Although lymph node dissection was performed, the presence of microscopic cancer-positive surgical stumps was confirmed.
View Article and Find Full Text PDFWe analyzed the prognosis of patients with positive lavage cytology, excluding other unresectable factors.From 2002 to 2008, 76 advanced gastric cancer patients positive for malignant cells(CY1)were investigated for our study.There were 60 patients undergoing gastric cancer surgery.
View Article and Find Full Text PDFIf hepatic or pulmonary metastases from colorectal cancer are resectable, we perform the operation, and the 5-year survival rate is 40-50%. Median survival time is over 20 months recently for systemic chemotherapy. However, surgical treatment is the only way to obtain a cure.
View Article and Find Full Text PDFGan To Kagaku Ryoho
December 2010
The number of surgeries for colorectal cancer in elderly patients is increasing in correspondence to Japan's aging society. It is important to evaluate the patient's condition in order to carry out operations safely. The Onodera index (Onodera index in order (PNI: prognostic nutritional index)=serum alb value × 10+the lymphocyte counts of peripheral blood) is a simple and useful tool for choosing the method of operation.
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