Correlation between the number of segmental chromosome aberrations and the age at diagnosis of diploid neuroblastomas without MYCN amplification.

Background: In neuroblastomas (NBs) without MYCN amplification, segmental chromosome aberrations SCAs such as 1p loss, 11q loss, and 17q gain have been suggested to be associated with the prognosis of the patients. We assessed the correlation between the number of SCAs and other biological factors in primary NBs samples.

Method: The status of SCAs in 54 primary NBs samples was analyzed using the single-nucleotide polymorphism (SNP) array (Human CMV370-Duo; Illumina, San Diego, CA).

Surgical intervention strategies for pediatric ovarian tumors: experience with 60 cases at one institution.

Purpose: The aim of this study was to assess the surgical intervention strategies for pediatric ovarian tumors.

Methods: The clinical features and treatment were analyzed for 60 children with ovarian tumors treated at our institution between 2000 and 2010.

Results: Twenty-one of the 60 patients were prenatally diagnosed neonatal cases with cystic lesions.