Publications by authors named "Ryoji Nakano"
Article Synopsis
- Immune checkpoint inhibitors (ICIs) have shown effectiveness in treating pleural mesothelioma, and the tumor microenvironment (TME) plays a crucial role in predicting responses to these treatments.
- A study analyzed surgical specimens from 22 patients treated with nivolumab, finding that higher densities of CD8 T cells near tumor cells were linked to better treatment responses.
- Conversely, regulatory T cells were found farther from tumor cells in responding patients, indicating that the spatial arrangement of immune cells in the TME could serve as a potential predictor for ICI effectiveness in this cancer type.
The patient was a 67-year-old male undergoing maintenance hemodialysis due to chronic renal failure caused by diabetic nephropathy. A left upper lobe resection was carried out for non-small cell lung cancer of the left upper lobe. It was histologically confirmed as pleomorphic carcinoma pT3N0M0, Stage ⅡB.
View Article and Find Full Text PDFCases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opacification in the lower lobe of the right lung.
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