Publications by authors named "Ryohei Nomura"

Background: Preprocedural detection of the running course of the right pericardiophrenic bundles (PBs) is considered to be useful in preventing phrenic nerve (PN) injury during catheter ablation for atrial fibrillation (AF). However, previous studies using the arterial phase of contrast-enhanced computed tomography (CT) reported a relatively low right PBs detection rate.

Methods: This study included 63 patients with AF who underwent catheter ablation and preoperative contrast-enhanced CT imaging of the venous and arterial phases (66.

View Article and Find Full Text PDF

Clinical outcomes after catheter ablation in patients with reduced left ventricular (LV) ejection fraction (EF) and atrial fibrillation (AF) remain unclear. This study aimed to explore the clinical outcomes of patients with arrhythmia-induced cardiomyopathy (AIC) and the influence of pharmacological treatment on clinical outcomes in patients with AIC after the procedure. Ninety-six patients with AF with a reduced LVEF (LVEF < 50%, 66.

View Article and Find Full Text PDF

Aims: We investigated the effects of door-to-tolvaptan (D2T) time on short-term urine volume and in-hospital clinical outcomes in patients with acute heart failure (AHF).

Methods And Results: Patients with AHF, treated with tolvaptan at two hospitals, were enrolled in this retrospective observational study. The D2T time was defined as the time elapsed from the arrival of a patient at a participating hospital to the first administration of tolvaptan.

View Article and Find Full Text PDF
Article Synopsis
  • This study explores the complex mechanisms of atrial fibrillation (AF) and how different activation patterns can impact outcomes after treatment.
  • Researchers examined 55 AF patients before ablation, focusing on the nonpassively activated ratio of various atrial segments to understand recurrence risk.
  • Results show that specific activation patterns, especially in the left atrium, were significant predictors of whether patients would experience recurrent AF after ablation, suggesting mapping may help guide treatment decisions.
View Article and Find Full Text PDF

Successful atrial fibrillation (AF) ablation can improve reduced left ventricular ejection fraction (LVEF) with AF, which is defined as arrhythmia-induced cardiomyopathy (AIC). However, it is difficult to pre-procedurally predict the presence of AIC. We aimed to explore the pre-procedural predictors of AIC in patients with AF and reduced LVEF.

View Article and Find Full Text PDF
Article Synopsis
  • * A library of surgical videos was evaluated by 51 experts to assess various factors affecting surgical difficulty, analyzing their agreement on the difficulty ratings.
  • * The findings led to the development of a new surgical difficulty grading system, which aims to provide a standardized and objective way to evaluate the complexity of LC procedures.
View Article and Find Full Text PDF
Article Synopsis
  • Terminal ileum diverticulitis is a rare condition that often mimics acute appendicitis, making diagnosis and treatment complex.
  • The report details four cases of terminal ileum diverticulitis, including varying presentations, treatment approaches (both conservative and surgical), and pathology findings.
  • All patients experienced right lower quadrant pain, with CT diagnoses supporting three cases and abscess drainage in one, highlighting the need for careful evaluation in similar clinical situations.
View Article and Find Full Text PDF

We report a resected case of cancer at the ileum of the blind loop. An 81-year-old male underwent an appendectomy for acute appendicitis and an ileotransverse colostomy for postoperative obstruction when he was 14 years old. He underwent radiation therapy for prostate cancer when he was 75 years old.

View Article and Find Full Text PDF
Article Synopsis
  • Sclerosing angiomatoid nodular transformation (SANT) is a rare benign spleen lesion, highlighted in a case of a middle-aged woman with early breast cancer.
  • The lesion was asymptomatic and diagnosed only after a laparoscopic splenectomy.
  • The case emphasizes that a splenic mass found during cancer follow-ups may not mean metastasis; SANT must be considered in such cases.
View Article and Find Full Text PDF

Purpose: Laparoscopic transabdominal preperitoneal inguinal hernia repair (TAPP) is technically difficult and not infrequently followed by postoperative complications and pain, especially when performed by inexperienced surgeons. To simplify TAPP and reduce postoperative pain, we devised a novel procedure whereby TAPP is carried out after the inguinal preperitoneal infiltration of diluted lidocaine and epinephrine saline solution and carbon dioxide gas (tumescent TAPP). This report introduces the concept of tumescent TAPP and summarizes its operative results.

View Article and Find Full Text PDF

We describe the case of a patient with a diaphragmatic hernia associated with radiofrequency ablation for hepatocellular carcinoma who was successfully treated by laparoscopic surgery. A 62-year-old man with a long history of hepatitis C-induced liver cirrhosis was admitted to our institution because of recurrent postprandial periumbilical pain. Eight years earlier, he had undergone radiofrequency ablation for hepatocellular carcinoma at hepatic segment VIII.

View Article and Find Full Text PDF

Here, we describe a case of a retroperitoneal liposarcoma successfully managed by laparoscopic surgery. A 72-year-old man underwent abnormal hypertension screening using computed tomography (CT), which revealed a low-density mass measuring 7 cm in diameter in the retroperitoneal space. We diagnosed the mass as a liposarcoma before the operation.

View Article and Find Full Text PDF

Although mesothelin is highly expressed in epithelial mesotheliomas, and also in adenocarcinomas of the ovary and pancreas, the clinical significance of mesothelin in cholangiocellular carcinoma (CC) has not been reported, and its biologic features are largely unknown. In the present study, mesothelin expression was evaluated in 25 patients with CC using a well-characterized mesothelin monoclonal antibody (5B2). A total of 8 of the 25 patients with CC (32%) showed mesothelin immunoreactivity.

View Article and Find Full Text PDF

A 76-year-old woman was diagnosed of mucinous cystadenocarcinoma of the appendix. Since there was wide direct invasion into the right psoas muscle, she was judged as inoperable although she had no bowel obstruction. She was received FOLFIRI and bevacizumab treatment.

View Article and Find Full Text PDF

A 60-yr-old man having hepatitis C virus-associated liver cirrhosis and hepatocellular carcinoma underwent living donor liver transplantation using a left liver graft. On post-operative day 20, the patient developed a large amount of ascites and hypovolemic shock because of decreased venous return. Emergency laparotomy revealed that fixation of the round ligament to the abdominal wall was loose, and free movement of the graft into the right subphrenic space had caused twisting the hepatic vein.

View Article and Find Full Text PDF

From the photosynthetic green sulfur bacterium Chlorobium tepidum (pro synon. Chlorobaculum tepidum), we have purified three factors indispensable for the thiosulfate-dependent reduction of the small, monoheme cytochrome c(554). These are homologues of sulfur-oxidizing (Sox) system factors found in various thiosulfate-oxidizing bacteria.

View Article and Find Full Text PDF

Objective: To determine the effects of pancreatoduodenectomy on hepatic fat content, hepatic CT attenuation was evaluated after pancreatoduodenectomy.

Conclusion: Pancreatoduodenectomy had a significant influence on hepatic fat content and was associated with frequent occurrence of hepatic steatosis, which was easily recognized with CT.

View Article and Find Full Text PDF

Zebrafish pectoral fin bud formation is an excellent model for studying morphogenesis. Fibroblast growth factors (Fgfs) and sonic hedgehog (shh) are essential for pectoral fin bud formation. We found that Fgf16 was expressed in the apical ectodermal ridge (AER) of fin buds.

View Article and Find Full Text PDF