Publications by authors named "Ryobu Tachi"
Int J Bipolar Disord
July 2023
Article Synopsis
- The study investigates the role of mitochondrial genetic variants in the development of bipolar disorder (BD), schizophrenia (SZ), and psychotic disorders (PSY) in a Japanese population, highlighting that previous research primarily focused on individuals of European ancestry.
- Using quality control methods, researchers analyzed 45 genetic variants in 420 participants (BD patients, SZ patients, and healthy controls) to identify associations with the disorders.
- Four specific variants showed significant associations with BD and PSY, particularly the rs200044200 variant, which was found only in BD patients, suggesting mitochondrial dysfunction may play a role in the pathogenesis of these disorders.
