Embedding Bifurcations into Pneumatic Artificial Muscle.

Harnessing complex body dynamics has long been a challenge in robotics, particularly when dealing with soft dynamics, which exhibit high complexity in interacting with the environment. Recent studies indicate that these dynamics can be used as a computational resource, exemplified by the McKibben pneumatic artificial muscle, a common soft actuator. This study demonstrates that bifurcations, including periodic and chaotic dynamics, can be embedded into the pneumatic artificial muscle, with the entire bifurcation structure using the framework of physical reservoir computing.

Public attitudes and intentions toward engaging in reintroduction of wolves to Japan.

Reintroducing apex predators is an important approach in ecosystem restoration; however, it is challenging. Wolves (Canis lupus) were exterminated in Japan around 1900, and since then, there has been a lack of top predators throughout the country. Currently, the wild ungulate population is increasing, causing agricultural and forest damage.

Valuation of student-led agricultural activities at university: comparison of willingness to pay with inferred values.

Agricultural fields in university campuses can improve urban nutrition security, increase greenery, and provide opportunities for students to grow crops and enhance self-management skills. We conducted student surveys among freshmen in two different years (2016 and 2020) to understand their willingness to pay (WTP) for donations toward student-led agricultural activities. In order to mitigate the social desirability bias, we also asked students' inferred WTP and compared that with conventional WTP.

AU-1 from Agavaceae plants causes transient increase in p21/Cip1 expression in renal adenocarcinoma ACHN cells in an miR-34-dependent manner.

Here, we show that AU-1, spirostanol saponin isolated from Agavaceae plants, causes a transient increase in cyclin-dependent kinase inhibitor (CDKI) p21/Cip1 through the upregulation of miRNAs, miR-34 and miR-21. AU-1 stimulated p21/Cip1 expression without exerting cytotoxicity against different types of carcinoma cell lines. In renal adenocarcinoma ACHN cells, AU-1 transiently elevated the expression level of p21/Cip1 protein without marked increases in p21/Cip1 mRNA levels.

Cardiac Resynchronization Therapy-Induced Cardiac Index Increase Measured by Three-Dimensional Echocardiography Can Predict Decreases in Brain Natriuretic Peptide.

Objectives: First, to examine the perioperative association between increased cardiac index (CI) measured using three-dimensional echocardiography (CI3D), two-dimensional echocardiography (CI2D), and FloTrac/Vigileo (CIFT) (Edwards Lifesciences, Irvine, CA) after cardiac resynchronization therapy (CRT) and decreased brain natriuretic peptide (BNP) 6 months after CRT. Second, to evaluate the accuracy and tracking ability of CI2D and CIFT.

Design: A prospective clinical study.

Large myxoma causing cardiac arrest during surgery.

The patient was a 67-year-old woman with a history of worsening dyspnea over several months. Cardiac echocardiography showed a large, mobile left atrial myxoma. Emergency surgery was performed.