Analysis of Speech Features in Alzheimer's Disease with Machine Learning: A Case-Control Study.

Background: Changes in the speech and language of patients with Alzheimer's disease (AD) have been reported. Using machine learning to characterize these irregularities may contribute to the early, non-invasive diagnosis of AD.

Methods: We conducted cognitive function assessments, including the Mini-Mental State Examination, with 83 patients with AD and 75 healthy elderly participants, and recorded pre- and post-assessment conversations to evaluate participants' speech.

Edible plant oil (EPO)-consumption activity of the isolate Fusarium keratoplasticum EN01 and other relative Fusarium species.

Edible oil is used in humans' daily lives, and the degradation of edible oil is a key process in sewage water treatment and in compost production from food wastes. In this study, a mixed microbial strain EN00, which showed high edible plant oil (EPO)-consumption activity, was obtained from soil via enrichment cultivation. A fungal strain EN01 was isolated from EN00 and relegated to Fusarium keratoplasticum, based on the nucleotide sequences of the TEF1-α gene.

Highly Efficient Near-Infrared Electrofluorescence from a Thermally Activated Delayed Fluorescence Molecule.

Near-IR organic light-emitting diodes (NIR-OLEDs) are potential light-sources for various sensing applications as OLEDs have unique features such as ultra-flexibility and low-cost fabrication. However, the low external electroluminescence (EL) quantum efficiency (EQE) of NIR-OLEDs is a critical obstacle for potential applications. Here, we demonstrate a highly efficient NIR emitter with thermally activated delayed fluorescence (TADF) and its application to NIR-OLEDs.

Precise Exciton Management of Quaternary Emission Layers for Highly Stable Organic Light-Emitting Diodes Based on Thermally Activated Delayed Fluorescence.

Simultaneous achievement of both high electroluminescence efficiency and high operational stability in organic light-emitting diodes (OLEDs) is required for their use in various practical applications. Although OLEDs based on thermally activated delayed fluorescence-assisted fluorescence (TAF) are considered to possess a promising device architecture to exploit the full potential of OLEDs, the operational stability of such systems still requires further improvement. In this study, a quaternary emission layer consisting of a combination of TAF and mixed-host systems is developed.

Exploiting Singlet Fission in Organic Light-Emitting Diodes.

Harvesting of both triplets and singlets yields electroluminescence quantum efficiencies of nearly 100% in organic light-emitting diodes (OLEDs), but the production efficiency of excitons that can undergo radiative decay is theoretically limited to 100% of the electron-hole pairs. Here, breaking of this limit by exploiting singlet fission in an OLED is reported. Based on the dependence of electroluminescence intensity on an applied magnetic field, it is confirmed that triplets produced by singlet fission in a rubrene host matrix are emitted as near-infrared (NIR) electroluminescence by erbium(III) tris(8-hydroxyquinoline) (ErQ ) after excitonic energy transfer from the "dark" triplet state of rubrene to an "emissive" state of ErQ , leading to NIR electroluminescence with an overall exciton production efficiency of 100.

Long-lived efficient delayed fluorescence organic light-emitting diodes using n-type hosts.

Organic light-emitting diodes have become a mainstream display technology because of their desirable features. Third-generation electroluminescent devices that emit light through a mechanism called thermally activated delayed fluorescence are currently garnering much attention. However, unsatisfactory device stability is still an unresolved issue in this field.

Near-Infrared Electrophosphorescence up to 1.1 µm using a Thermally Activated Delayed Fluorescence Molecule as Triplet Sensitizer.

A tenfold improvement in the external electroluminescence quantum efficiency of NIR electrophosphorescence is demonstrated compared to devices with conventional fluorescent materials as host, by applying the concept of thermally activated delayed fluorescence to achieve an emitter layer capable of efficient spin conversion. This device architecture can maximize the performance of an organic-semiconductor-based NIR light source.

Molecular and enzymatic characterization of a subfamily I.4 lipase from an edible oil-degrader Bacillus sp. HH-01.

An edible-oil degrading bacterial strain HH-01 was isolated from oil plant gummy matter and was classified as a member of the genus Bacillus on the basis of the nucleotide sequence of the 16S rRNA gene. A putative lipase gene and its flanking regions were cloned from the strain based on its similarity to lipase genes from other Bacillus spp. The deduced product was composed of 214 amino acids and the putative mature protein, consisting of 182 amino acids, exhibited 82% amino acid sequence identity with the subfamily I.