Publications by authors named "Ryo Mitoma"

Article Synopsis
  • Researchers developed a new PET tracer, [C]K-2, that allows for the visualization and measurement of AMPAR density in the brains of living human patients, which is important for understanding neurotransmission in psychiatric disorders.
  • The study involved 149 patients with various psychiatric disorders (like schizophrenia and bipolar disorder) and 70 healthy individuals, revealing correlations between AMPAR density and symptom severity.
  • The findings highlight unique patterns of AMPAR distribution across different psychiatric disorders, suggesting potential new approaches for diagnosing and treating these conditions based on biological mechanisms.
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Schizophrenia was initially defined as "dementia praecox" by E. Kraepelin, which implies progressive deterioration. However, recent studies have revealed that early effective intervention may lead to social and functional recovery in schizophrenia.

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