Publications by authors named "Ryo Itamura"
Article Synopsis
- Cefcapene pivoxil hydrochloride is an antibiotic commonly used by pregnant women, but its safety during the first trimester has not been previously studied.
- This research compared the incidence of major malformations in infants born to women who took this antibiotic (2.6%) versus those who used control drugs (1.8%), using data from two Japanese facilities between 1988 and 2017.
- The study found no significant difference in major malformation rates between the groups, suggesting that cefcapene pivoxil hydrochloride does not increase malformation risks and can inform healthcare providers on medication choices during pregnancy.
Inadvertent leakage of medications with vesicant properties can cause severe necrosis in tissue, which can have devastating long-term consequences. The aim of this study was to evaluate the extent of extravasation injury induced by thiopental and propofol, and the effects of cooling or warming of local tissue on extravasation injury at macroscopic and histopathologic levels. Rats were administered intradermally thiopental (2.
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