Publications by authors named "Ryo Higuchi"

Objectives: As many patients with osteoporosis remain undiagnosed, we aimed to develop a simple method to efficiently screen for osteoporosis using a combination of anteroposterior hip X-ray assessment and the Osteoporosis Self-Assessment Tool for Asians (OSTA), which is calculated as (body weight - age) × 0.2.

Methods: One hundred Japanese women (age: 73 ± 11 years, body weight: 54.

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A novel Signal Processing algorithm based on the combination of a Wavelet Transform Analysis and Image Processing techniques is designed for assessing the delamination detectability of Lamb Waves generated with an innovative fully non-contact system in CFRP plates. Several Damage Indexes are extracted from the wavefields in spatial-time-frequency domain and plotted as surface cartographies to visualise their ability to size and localise artificial delaminations. Results show that the algorithm is efficient for characterising the waves propagation and that sophisticated Image comparison indexes show better ability to detect the artificial defects and to recognise healthy zones despite signal measurement and calculation uncertainties.

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Article Synopsis
  • Diagnosis and treatment of osteoporosis are crucial for successful hip surgery outcomes, and measuring bone mineral density (BMD) via DXA is the established method, but access can be limited.* -
  • The study analyzed 1378 female patients undergoing hip surgery, assessing the correlation between BMD and the Osteoporosis Self-assessment Tool for Asians (OSTA) score, finding a strong correlation and establishing a cut-off score that effectively predicts osteoporosis.* -
  • Results indicate that the OSTA tool can help screen for osteoporosis in at-risk patients before surgery, enabling targeted investigations and potentially improving patient outcomes.*
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In this study, the cooling rate-dependent properties of polyphenylene sulfide (PPS) and carbon fiber reinforced PPS (CF/PPS) manufactured at different cooling rates (1, 5, and 10 °C/min) are presented. The cooling rate-dependent densities of neat PPS and CF/PPS were determined based on the Archimedes' principle. The coefficients of thermal expansion (CTEs) were determined using a thermomechanical analyzer.

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Article Synopsis
  • CFRP structures, like aircraft, can suffer both visible and hidden damage from foreign object impacts, leading to a reduction in strength.
  • Despite external damage sometimes being minimal, internal issues like matrix cracks and delamination can significantly affect the material's integrity.
  • A dataset has been created to help predict internal damage based solely on surface damage profiles using Machine Learning, providing valuable resources for researchers and engineers studying CFRP impact behavior.
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Background: Elective orthopaedic surgery has been severely curtailed because of coronavirus disease, 2019. There is scant scientific evidence to guide surgeons in assessing the protocols that must be implemented before resuming elective orthopaedic surgery safely after the second wave of the coronavirus disease, 2019.

Methods: A retrospective review of elective orthopaedic surgeries performed between May 15, 2020, and November 20, 2020, was conducted.

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Neural progenitor cells (NPCs), which are apicobasally elongated and densely packed in the developing brain, systematically move their nuclei/somata in a cell cycle-dependent manner, called interkinetic nuclear migration (IKNM): apical during G2 and basal during G1. Although intracellular molecular mechanisms of individual IKNM have been explored, how heterogeneous IKNMs are collectively coordinated is unknown. Our quantitative cell-biological and in silico analyses revealed that tissue elasticity mechanically assists an initial step of basalward IKNM.

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Oxidative stress caused by reactive oxygen species is considered a major mediator of tissue and cell injuries in various neuronal conditions, including neurological emergencies and neurodegenerative diseases. Molecular hydrogen is well characterized as a scavenger of hydroxyl radicals and peroxynitrite. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings.

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Actin cables of budding yeast are bundles of F-actin that extend from the bud tip or neck to the mother cell tip, serve as tracks for bidirectional cargo transport, and undergo continuous movement from buds toward mother cells [1]. This movement, retrograde actin cable flow (RACF), is similar to retrograde actin flow in lamellipodia, growth cones, immunological synapses, dendritic spines, and filopodia [2-5]. In all cases, actin flow is driven by the push of actin polymerization and assembly at the cell cortex, and myosin-driven pulling forces deeper within the cell [6-10].

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