With the increasing availability of smartphones, many tobacco researchers are exploring smartphone-delivered mobile smoking interventions as a disseminable means of treatment. Most effort has been focused on the development of smartphone applications (apps) to conduct mobile smoking research to implement and validate these interventions. However, developing project-specific smartphone apps that work across multiple mobile platforms (e.
View Article and Find Full Text PDFIntroduction: In smoking cessation clinical trials, timeline followback (TLFB) interviews are widely used to track daily cigarette consumption. However, there are no standard tools for calculating abstinence based on TLFB data. Individual research groups have to develop their own calculation tools, which is not only time- and resource-consuming but might also lead to variability in the data processing and calculation procedures.
View Article and Find Full Text PDFPrimases are DNA-dependent RNA polymerases found in all cellular organisms. In bacteria, primer synthesis is carried out by DnaG, an essential enzyme that serves as a key component of DNA replication initiation, progression, and restart. How DnaG associates with nucleotide substrates and how certain naturally prevalent nucleotide analogs impair DnaG function are unknown.
View Article and Find Full Text PDFThe implementation of the recent act to amend the law on hospitals, patient health and territories (HPST Law) completes the reform of the organization and governance of health facilities, which was announced in 2002 by the "Hospital 2007" plan. What kind of assessments and perspectives can be considered and envisaged for these Hospital Activity Poles? We compared our experience with a review of the professional and scientific literature in order to stimulate answers to these questions for advocacy purposes prior to the Act's implementation. The hospital's cluster of activities should reinforce--not call into question the core activities and the financial stability of the facility, while respecting the contract on agreed objectives and the necessary means and resources to meet the health needs of the catchment population as well as national priorities.
View Article and Find Full Text PDFPurpose: To determine the costs related to the embolization of intracranial aneurysms compared to "rates per activity" (T2A) reimbursements.
Materials And Methods: The hospital admissions of patients with intracranial aneurysms treated with embolization and classified under diagnosis-related group (DRG) 01K02Z in 2007 were included. The costs related to the single-use devices, neurointerventional suite and hospital stay were calculated by analytical accounting.
Purpose: To determine the utility of computed tomographic (CT) enteroclysis for characterization of the status of the anastomotic site in patients with Crohn disease who had previously undergone ileocolic resection.
Materials And Methods: Written informed consent was prospectively obtained from all patients, and the institutional review board approved the study protocol. CT enteroclysis findings in 40 patients with Crohn disease who had previously undergone ileocolic resection were evaluated independently by two readers.
Objectives: To administer a social handicap questionnaire associated with French DRGs (PMSI) to determine the social handicaps of a population hospitalized in a public health establishment and to measure the cost implications for the establishment due to increased length of stay (DMS).
Method: A prospective pilot study has been carried out in the Lariboisière-Fernand Widal Hospital Group in Paris targeting users 50 or more years old hospitalized for short stays in medicine, surgery and obstetrics. Data of the PMSI and answers to the questionnaire for hospitalisations longer than 24 hours have been exploited.
In the context of implementing hospital reforms, the objective of this work was to compare practice in relation to evidence-based guidelines and recommendations for good practice in diabetes screening and management. Laboratory test consumption was determined for patients hospitalized for diabetes in 2005 in three public hospitals (one civilian, two military) taking care of diabetic patients and performing related biological tests. For the 395 admissions in these three hospitals during 2005 [Diagnosis-related group (DRG) 10M02V "Diabetes, age 36 to 69 years without co-morbidity"], the average length of stay and the number of biological acts ["B"] performed were lower than those given by the French national health cost study scale and by the Montpellier University Hospital database.
View Article and Find Full Text PDFObjective: To determine the potential of helical CT for differentiating true lesions from pseudolesions in patients with fatty liver.
Methods: Helical CT of 44 patients with diffuse fatty liver (22 with true lesions; 22 with pseudolesions) were reviewed by two observers with regard to morphological features of visible lesions. Univariate analysis was used to detect discriminating criteria for the diagnosis of true lesions.
Purpose: To describe the computed tomographic (CT) enteroclysis features of uncomplicated celiac disease (CD) and to determine the most indicative appearance of this condition by using a retrospective case-control study.
Materials And Methods: This study had institutional review board approval. The CT enteroclysis examinations of 44 consecutive patients with proved uncomplicated CD (21 men, 23 women; mean age, 44.
Life-threatening intra-abdominal hemorrhage following ultrasonographically guided percutaneous renal biopsy is extremely rare and, most of the time, is due to renal vascular injury. Injury of other abdominal arteries during percutaneous renal biopsy is exceedingly rare. We report herein a case of left superior colonic artery injury during ultrasonographically guided percutaneous renal biopsy, which was responsible for pseudoaneurysm formation and subsequent intra-abdominal hemorrhage and gastrointestinal bleeding.
View Article and Find Full Text PDFThe objective of our retrospective study was to determine the MDCT-enteroclysis appearance of the appendix in patients with Crohn's disease and to correlate this appearance with the status of the disease. We reviewed the MDCT-enteroclysis examinations of 76 patients with Crohn's disease. Images were analyzed for visualization of the appendix, largest axial diameter of the appendix and degrees of enhancement.
View Article and Find Full Text PDFUnlabelled: Multi-detector row computed tomography (MDCT) offers an alternative to diagnostic coronary angiography for visualizing coronary arteries. The major limitation of recently published studies, aside from being monocentric in nature and the low number of patients included, is the selection of patients. These studies do not provide any answers for patients who are seen daily in cardiology consultation.
View Article and Find Full Text PDFGastrointestinal stromal tumors (GIST) arising from interstitial cells of Cajal, represent the first type of solid tumor, which is very sensitive to a specific molecularly targeted tyrosine kinase receptor blocker (i. e., imatinib).
View Article and Find Full Text PDFA recent study to measure social disability used the results of a questionnaire administered to 696 patients between March 14th and April 7th 2007 which showed that three-quarters of the population surveyed have a social disability. Major determinants of social disadvantage are found using three specific indicators: income, assets and home-interior comfort. A greater deterioration of poor health status was not particularly noted within the most socially disadvantage group of patients, and social disability did not lead to actual over-consumption of medical products or services.
View Article and Find Full Text PDFAcute intestinal bleeding is a severe condition, with a mortality rate of up to 40% in case of associated hemodynamic instability. The diagnosis of acute intestinal bleeding is often challenging and to date, there is no definite consensus upon the most appropriate technique for this specific diagnosis. This pictorial essay illustrates our preliminary use of multiplanar (MPR) and maximum intensity projection (MIP) reformations using MDCT scanner with submillimeter and isotropic voxels as an adjunct to axial images in patients with acute intestinal bleeding.
View Article and Find Full Text PDFPhysical activity and sports are considered as one of the determinants of health. The aim of this study is to review the rationale for the formulation of this public health issue and its integration in national action plans. The study shows that fourteen national programmes were drafted and implemented between 2001 and 2006 by seven institutions.
View Article and Find Full Text PDFThe purpose of this study was to report our experience in the management of severe primary postpartum hemorrhage due to genital tract laceration following operative vaginal delivery with forceps using pelvic transcatheter arterial embolization (TAE). Ten women (mean age, 31.9 years) with severe primary postpartum hemorrhage due to genital tract laceration after operative delivery with forceps were treated with TAE.
View Article and Find Full Text PDFBackground: Our objective was to retrospectively determine the frequency with which CT enteroclysis (CTE) shows abdominopelvic extra-enteric abnormalities and to analyze how such findings had actually and prospectively affected patient's care.
Methods: The CTE examinations of 430 consecutive patients were retrospectively and blindly reviewed for the presence of possible pathologic conditions that might have affected abdominopelvic organs other than the small bowel. Extra-enteric abnormalities were categorized as negligible or important and correlated with patient's outcome and thus classified as having or not influenced patient's care.
Objectives: Would a social handicap questionnaire with French DRG (PMSI) make it possible to know social disability parturients vaginal childbirth in a public health loss of revenue by increasing the average length of stay during the hospitalization of patients precarious?
Patients And Methods: The questionnaire of the social handicap consisted of 14 indicators associated to classify at the admission each patient in three categories of social handicap.
Results: The administration of a questionnaire of social handicap was carried out for 127 women giving birth by low way. Three quarters of the studied population have a strong social handicap and 18% present a means of it.
Background: According to the framework legislation promulgated as part of the reform of finance laws in France, quality is a mandatory feature of all governmental actions. In this context, this work was conducted to assess the construction cost of a national health program designed to promote physical and sports activities and prevent doping behaviors. This program was considered to have the characteristic features of a successful governmental health intervention.
View Article and Find Full Text PDFCurrent protocols for myeloma patients require more than one autologous transplant. We performed a retrospective study to determine the cost-effectiveness of large volume leukapheresis (LVL) compared with standard volume leukapheresis (SVL) collection when two transplants are required. We evaluated 87 patients who underwent a cumulative total of 260 LVL and SVL collections.
View Article and Find Full Text PDFWe report one case of replaced right hepatic artery coursing ventral to the portal vein. This variation, which was demonstrated by 64-row CT angiography and three-dimensional reformatted images, has never been reported. Surgeons involved in hepatic and biliopancreatic procedures should be aware of this possible variation, which has important surgical implications.
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