[Echocardiographic evaluation of left ventricular function in patients after myocardial infarction treated with enalapril].

The studies were carried out in 30 patients (24 men and six women) aged 40-56 years, mean age 51 years after myocardial infarction in whom enalapril in doses 5-10 mg daily, mean dose 8,5 mg daily was added to drugs used as yet. This drug was administered for six weeks. The patients had myocardial infarction 6-18 months before their inclusion to the studies.

[Effect of physical exercise on aortic blood flow in patients with primary arterial hypertension].

In 40 patients (30 men and 10 women) aged to 21 to 48 years (mean 42 years) with essential hypertension stage II, according to WHO classification, blood flow was recorder in the ascending aorta by Doppler echocardiography. The investigation was done in erect position, at rest, and during 30 seconds of each phase of exercise on moving track. The control group comprised 20 healthy males aged 23-45 years (mean 38 years).

[Effects of verapamil and propranolol on the left-ventricular diastolic function in patients with primary arterial hypertension].

Mitral flow was assessed by Doppler echocardiography in patients with systemic hypertension. The study was carried out on 40 patients (27 men and 13 women) aged 24-50 years, mean 43 years with essential hypertension stage II according to WHO classification. No patient had other heart disease or diabetes.

[Curves of aortic and mitral flow recorded by Doppler echocardiography in patients with primary hypertension].

The systolic and diastolic left-ventricular myocardium function was assessed by Doppler echocardiography in patients with hypertension. The study was carried out on 40 patients (26 men and 14 women) aged 21-50 years (mean 45 years) with essential hypertension, stage II according to WHO classification. The control group comprised 20 healthy subjects aged 19-48 years (mean 43 years).

[Dynamics of left ventricular contraction in patients with myocardial infarction after hospital rehabilitation, assessed by Doppler echocardiography].

The reported study was carried out in 30 men with myocardial infarction. In all cases after completion of rehabilitation treatment in hospital the exercise test was done on cycle ergometer and echocardiographic examination was performed (TM, 2D and Doppler). The patients were divided into two groups depending on the size of the necrotic zone (limited or extensive infarction in ECG) and physical fitness (low and high) determined by means of the PCW-170 test.

[Effect of the treatment with propranolol and pindolol on selected hemodynamic parameters in patients with primary arterial hypertension].

On the basis of echocardiographic investigations changes were analysed of certain haemodynamic parameters in 40 patients aged 21-50 years, mean 44 years, with primary arterial hypertension in stage II according to WHO classification. All patients were randomly chosen to receive for 6-9 weeks propranolol 120-480 mg daily, mean dose 280 mg, or pindolol 10-35 mg daily, mean dose 22 mg daily. The changes developing during the treatment with both drugs in relation to the initial values included the mean arterial blood pressure, the heart rate, the index of cardiac output and the systolic left-ventricular tension.

[Value of Doppler echocardiography in evaluating pulmonary arterial pressure in patients with mitral valve defect].

In 40 patients aged 25-52 years (mean 36 years) with mitral valve disease but without overt circulatory failure haemodynamic studies and echocardiographic examinations were carried out recording the blood flow in the pulmonary artery and the blood flow through the tricuspid valve by pulsating and continuous-wave methods. From the obtained curves the time was calculated from the beginning of the flow to its maximum (TPV), the pre-ejection time (RPEP) and the right-ventricular ejection time (RVET), and the indices TPV/RVET and RPEP/RVET. Moreover, in 14 patients with coexistent insufficiency of the tricuspid valve the systolic pressure in the pulmonary artery was calculated by determining the systolic gradient across the tricuspid valve.

[Value of sustonit in the treatment of patients with stable angina pectoris].

The clinical trial was carried out in 40 men with stable angina receiving for three weeks Sustonit mite or forte. Before and after three weeks of the treatment the exercise test was done on cycle ergometer, followed by echocardiography (for evaluation of left ventricular function) noting also the number of anginal pains and the number of nitroglycerin tablets taken as emergency treatment. In the light of the obtained results it was estimated that Sustonit reduced anginal pains in 82.