HLA and Nasal Polyposis Susceptibility: A Meta-analysis of Worldwide Studies.

Objectives: Nasal polyposis (NP) is a common and recurrent condition of the sinonasal cavity which has significant impact on patients' quality of life. NP pathophysiology involves a complex interplay of genetic, environmental, and immunological factors. Several studies have explored the association between human leukocyte antigen (HLA) class II alleles and NP, but the results have been conflicting.

Endoscopic Versus Microscopic Transcanal Resection of Glomus Tympanicum: A Retrospective Comparative Study.

Objective: Comparison of outcomes of microscopic and endoscopic resection of glomus tympanicum (GT) tumors.

Study Design: Retrospective case review.

Setting: Single tertiary referral center.

Bullous Pemphigoid and Human Leukocyte Antigen (HLA)-DQA1: A Systematic Review.

Bullous pemphigoid (BP) is an autoimmune blistering disease that mainly affects the elderly. The human leukocyte antigen (HLA) system is believed to be one of the genetic factors involved in the development of BP. The connection between major histocompatibility complex class II, specifically HLA-DQA1, and BP remains inconclusive.

Defining Hearing Loss Severity Based on Pure-Tone Audiometry and Self-Reported Perceived Hearing Difficulty: National Health and Nutrition Examination Survey.

Background:  There is a well-known metric to describe average/normal vision, 20/20, but the same agreed-upon standard does not exist for hearing. The pure-tone average has been advocated for such a metric.

Purpose:  We aimed to use a data-driven approach to inform a universal metric for hearing status based on pure-tone audiometry and perceived hearing difficulty (PHD).