An Integrated Rapid Response Model for Pediatric Patients Requiring In-Patient Medical Stabilization: Lessons Learned to Enable Regional Capacity Building.

There was an unprecedented surge in admissions for medical stabilization of pediatric patients with eating disorders during the COVID-19 pandemic in Ontario. Eleven hospitals established an integrated rapid response model to ensure timely in-patient access for these patients. This population was cared for in re-allocated community hospital beds as a result of engaging hospital leadership, strengthening partnerships, consulting experts, leveraging existing resources and developing regional bed access strategies.

Mental states via possessive predication: the grammar of possessive experiencer complex predicates in Persian.

Persian possesses a number of stative complex predicates with 'to have' that express certain kinds of mental state. I propose that these be given a formal semantic treatment involving possession of a portion of an abstract quality by an individual, as in the analysis of property concept lexemes due to Francez and Koontz-Garboden (Language 91(3):533-563, 2015; Natural Language and Linguistic Theory 34:93-106, 2016; Semantics and morphosyntactic variation: Qualities and the grammar of property concepts, Oxford University Press, 2017). Augmented with an analysis of prepositional phrases introducing the target of the mental state and an approach to gradability in terms of measure functions (Wellwood in Measuring predicates, PhD dissertation, University of Maryland, College Park, 2014), the analysis explains various properties of possessive experiencer complex predicates, including the behavior of target phrases, the ability of the non-verbal element to be modified by a range of adjectives, the direct participation of the non-verbal element in comparative constructions, and the ability of degree expressions to modify both the non-verbal element and the VP containing the complex predicate.

Mapping the estrous cycle to context-specific extinction memory.

In Pavlovian renewal paradigms, intact female rats have previously failed to exhibit renewal of appetitive behavior after extinction. However, when treated with exogenous estradiol, female rats exhibit robust renewal behavior. The current study aims to investigate whether the estrous cycle can influence renewal of appetitive behaviors and activity in brain areas known to support the renewal effect.

Factors associated with car seat test failure in late preterm infants: A retrospective chart review.

Background: Professional organizations recommend car seat testing of preterm infants before discharge from hospital. Late preterm infants (LPIs, 34(0/7) to 36(6/7) weeks' gestational age) are at the greatest risk for failure, despite often being well.

Objective: To determine the incidence of car seat testing failure in LPIs and associative factors.

Soft Tissue Mobilization to Resolve Chronic Pain and Dysfunction Associated With Postoperative Abdominal and Pelvic Adhesions: A Case Report.

Study Design: Case report.

Background: Common complications from abdominal and pelvic surgery include adhesions and chronic pain. Laparoscopic adhesiolysis is sometimes used to reduce adhesions and related pain.

Baseline Examination Factors Associated With Clinical Improvement After Dry Needling in Individuals With Low Back Pain.

Study Design: Quasi-experimental.

Objectives: To explore for associations between demographic, patient history, and physical examination variables and short-term improvement in self-reported disability following dry needling therapy performed on individuals with low back pain (LBP).

Background: Dry needling is an intervention used with increasing frequency in patients with LBP; however, the characteristics of patients who are most likely to respond are not known.

Association between fraction of exhaled nitrous oxide, bronchodilator response and inhaled corticosteroid type.

Background: Fraction of exhaled nitrous oxide (FeNO) is a known marker of airway inflammation and a topic of recent investigation for asthma control in children.

Objective: To investigate the relationship among FeNO and bronchodilator response measured by spirometry and types of inhaled corticosteroids (ICS).

Methods: A one-year review of children tested with spirometry and FeNO in a regional pediatric asthma centre was conducted.

Severely elevated transaminases in an adolescent male with anorexia nervosa.

Anorexia nervosa (AN) is a serious disorder that is associated with numerous medical complications and affects both females and males. Severely elevated transaminases have been reported in adult and younger females. We report the first case of elevated transaminases in an adolescent male with AN.

Prevalence of hypothalamic-pituitary-adrenal axis suppression in children treated for asthma with inhaled corticosteroid.

Objective: To determine the prevalence of hypothalamic-pituitary-adrenal (HPA) axis suppression in asthmatic children on inhaled corticosteroids (ICS).

Methods: Clinical and demographic variables were recorded on preconstructed, standardized forms. HPA axis suppression was measured by morning serum cortisol levels and confirmed by low-dose adrenocorticotropic hormone stimulation testing.

Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful procedures.

Objective: Sweetening agents have been recommended in position statements and consensus documents for procedural pain management in neonates; however, it is not clear if this has resulted in widespread adoption in clinical practice. The objective of this study was to investigate unit-specific protocols for the use of sweetening agents.

Methods: Structured telephone survey with qualified personnel in special care (level II) nurseries and neonatal intensive care (level III) units across Canada.

Spectrum and management of hypertriglyceridemia among children in clinical practice.

Objectives: The prevalence and identification of hypertriglyceridemia in youths will likely will increase in the future as a consequence of childhood obesity and increased screening for dyslipidemias. We sought to review our clinical experience with hypertriglyceridemia, evaluate factors associated with increased triglyceride levels, and review treatment options to provide guidance for management.

Methods: Clinical review of data for all patients who had > or =1 elevated triglyceride level (>4 mmol/L [>350 mg/dL]) while being monitored in a specialized lipid disorders clinic was performed.

Prospective study of a noninvasive treatment for two common congenital toe abnormalities (curly/varus/underlapping toes and overlapping toes).

Objective: To assess, in the newborn, the efficacy of a standard taping treatment used in children for two selected congenital toe abnormalities (curly/varus/underlapping toes and overlapping toes), and compare the outcome with the available world literature.

Methods: All children referred by their family physician between January 2004 and January 2006 were included. The newborns were reviewed by one author (WGS) within 10 days of birth, assessed for severity, and the toes were taped in a standard manner if the abnormalities met the study criteria.

Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures.

Background: Sucrose is widely used to manage procedural pain in term newborns despite a lack of evidence of its effectiveness for different procedures and infant populations. Our objectives were to evaluate the effectiveness and safety of sucrose in newborns undergoing various medical procedures within 2 days of birth.

Methods: We performed a double-blind, randomized controlled trial.

Caregivers' responses to pain in their children in the emergency department.

Objective: To explore physiological and anxiety responses of caregivers who witness a venipuncture being performed on their child and the effects of caregivers' responses on child pain and distress.

Design: Observational study between March 13, 2006, and June 8, 2006.

Setting: Tertiary-level pediatric emergency department in Toronto, Ontario.

Children with autism: effect of iron supplementation on sleep and ferritin.

To determine if there is a relationship between low serum ferritin and sleep disturbance in children with autism spectrum disorder, an 8-week open-label treatment trial with oral iron supplementation was conducted as a pilot study. At baseline and posttreatment visits, parents completed a Sleep Disturbance Scale for Children and a Food Record. Blood samples were obtained.