Breast Cancer (Dove Med Press)
March 2024
Introduction: The study focuses on evaluating the immune responses generated by a novel microparticulate murine breast cancer vaccine.
Methods: The methodology included the use of a co-culture model of dendritic cells (DCs), and T-cells to evaluate the immunotherapeutic responses generated by the vaccine.
Results: The study observed that the dendritic cells expressed significantly higher levels of MHC I, MHC II, CD 40, and CD 80 cell surface markers in the presence of the vaccine microparticles than the controls (p<0.