Association between GRIN2A promoter polymorphism and recovery from concussion.

Objective: To determine genetic variability within the N-methyl-D-aspartate receptor 2A sub-unit (GRIN2A) gene promoter and its association with concussion recovery time. The hypothesis tested was that there would be a difference in allele and/or genotype distribution between two groups of athletes with normal and prolonged recovery.

Methods: DNA was extracted from saliva collected from a total of 87 athletes with a physician-diagnosed concussion.