Publications by authors named "Ryan Sokup"
Article Synopsis
- MSL breast cancers have mesenchymal traits and a poor prognosis, often being triple-negative with limited treatment options due to the presence of drug-resistant tumor cells.
- An inhibitor screen revealed that combining CHK1 inhibitors with BCL2 inhibitors significantly enhances treatment effectiveness for MSL breast cancers, leading to increased cancer cell death.
- The combination treatment induces DNA damage and cell-cycle issues in MSL breast cancer cells, suggesting that dual-targeting could improve outcomes for patients with this aggressive cancer type.
