Publications by authors named "Ryan S Mcginnis"

Objectives: Despite the development of efficacious wellness interventions, sustainable wellness behavior change remains challenging. To optimize engagement, initiating small behaviors that build upon existing practices congruent with individuals' lifestyles may promote sustainable wellness behavior change. In this study, we crowd-sourced helpful, flexible, and engaging wellness practices to identify a list of those commonly used for improving sleep, productivity, and physical, emotional, and social wellness from participants who felt they had been successful in these dimensions.

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Background: Mechanically ventilated Intensive Care Unit (ICU) patients often require wrist restraints, contributing to immobility and agitation, over-sedation, and delirium. The ® ® (Healthy Design, LLC), a novel restraint alternative, may be safe and facilitate greater mobility than traditional restraints.

Objective: This National Institutes of Health Small Business Technology Transfer (STTR) Program Grant-funded single-site Phase I feasibility study evaluated ® safety and feasibility in anticipation of a multi-site Phase II randomized controlled trial (RCT).

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Introduction: Wearable devices are rapidly improving our ability to observe health-related processes for extended durations in an unintrusive manner. In this study, we use wearable devices to understand how the shape of the heart rate curve during sleep relates to mental health.

Methods: As part of the Lived Experiences Measured Using Rings Study (LEMURS), we collected heart rate measurements using the Oura ring (Gen3) for over 25,000 sleep periods and self-reported mental health indicators from roughly 600 first-year university students in the USA during the fall semester of 2022.

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In response to a burgeoning pediatric mental health epidemic, recent guidelines have instructed pediatricians to regularly screen their patients for mental health disorders with consistency and standardization. Yet, gold-standard screening surveys to evaluate mental health problems in children typically rely solely on reports given by caregivers, who tend to unintentionally under-report, and in some cases over-report, child symptomology. Digital phenotype screening tools (DPSTs), currently being developed in research settings, may help overcome reporting bias by providing objective measures of physiology and behavior to supplement child mental health screening.

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Consumer wearables have been successful at measuring sleep and may be useful in predicting changes in mental health measures such as stress. A key challenge remains in quantifying the relationship between sleep measures associated with physiologic stress and a user's experience of stress. Students from a public university enrolled in the Lived Experiences Measured Using Rings Study (LEMURS) provided continuous biometric data and answered weekly surveys during their first semester of college between October-December 2022.

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Objective: Panic attacks are an impairing mental health problem that affects 11% of adults every year. Current criteria describe them as occurring without warning, despite evidence suggesting individuals can often identify attack triggers. We aimed to prospectively explore qualitative and quantitative factors associated with the onset of panic attacks.

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Postural instability is associated with disease status and fall risk in Persons with Multiple Sclerosis (PwMS). However, assessments of postural instability, known as postural sway, leverage force platforms or wearable accelerometers, and are most often conducted in laboratory environments and are thus not broadly accessible. Remote measures of postural sway captured during daily life may provide a more accessible alterative, but their ability to capture disease status and fall risk has not yet been established.

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Panic attacks are an impairing mental health problem that impacts more than one out of every 10 adults in the United States (US). Clinical guidelines suggest panic attacks occur without warning and their unexpected nature worsens their impact on quality of life. Individuals who experience panic attacks would benefit from advance warning of when an attack is likely to occur so that appropriate steps could be taken to manage or prevent it.

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Preeclampsia (PE) is a leading cause of maternal and perinatal death globally and can lead to unplanned preterm birth. Predicting risk for preterm or early-onset PE, has been investigated primarily after conception, and particularly in the early and mid-gestational periods. However, there is a distinct clinical advantage in identifying individuals at risk for PE prior to conception, when a wider array of preventive interventions are available.

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Childhood mental health disorders such as anxiety, depression, and ADHD are commonly-occurring and often go undetected into adolescence or adulthood. This can lead to detrimental impacts on long-term wellbeing and quality of life. Current parent-report assessments for pre-school aged children are often biased, and thus increase the need for objective mental health screening tools.

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Childhood mental health problems are common, impairing, and can become chronic if left untreated. Children are not reliable reporters of their emotional and behavioral health, and caregivers often unintentionally under- or over-report child symptoms, making assessment challenging. Objective physiological and behavioral measures of emotional and behavioral health are emerging.

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Childhood mental health problems are common, impairing, and can become chronic if left untreated. Children are not reliable reporters of their emotional and behavioral health, and caregivers often unintentionally under- or over-report child symptoms, making assessment challenging. Objective physiological and behavioral measures of emotional and behavioral health are emerging.

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Introduction: The transition to college is a period of elevated risk for a range of mental health conditions. Although colleges and universities strive to provide mental health support to their students, the high demand for these services makes it difficult to provide scalable, cost-effective solutions.

Objective: To address these issues, the present study aims to compare the efficacy of three different treatments using a large cohort of 600 students transitioning to college.

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Impairment in persons with multiple sclerosis (PwMS) can often be attributed to symptoms of motor instability and fatigue. Symptom monitoring and queued interventions often target these symptoms. Clinical metrics are currently limited to objective physician assessments or subjective patient reported measures.

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Typical assessments of balance impairment are subjective or require data from cumbersome and expensive force platforms. Researchers have utilized lower back (sacrum) accelerometers to enable more accessible, objective measurement of postural sway for use in balance assessment. However, new sensor patches are broadly being deployed on the chest for cardiac monitoring, opening a need to determine if measurements from these devices can similarly inform balance assessment.

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Preeclampsia (PE) is a leading cause of maternal and perinatal death globally and can lead to unplanned preterm birth. Predicting risk for preterm or early-onset PE, has been investigated primarily after conception, and particularly in the early and mid-gestational periods. However, there is a distinct clinical advantage in identifying individuals at risk for PE prior to conception, when a wider array of preventive interventions are available.

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Unlabelled: Panic attacks are an impairing mental health problem that impacts more than one out of every 10 adults in the United States (US). Clinical guidelines suggest panic attacks occur without warning and their unexpected nature worsens their impact on quality of life. Individuals who experience panic attacks would benefit from advance warning of when an attack is likely to occur so that appropriate steps could be taken to manage or prevent it.

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Article Synopsis
  • Falls are common among individuals with multiple sclerosis (PwMS), leading to health complications, and fluctuations in MS symptoms can make it hard to assess fall risk through standard biannual clinical visits.
  • Recent advancements in remote monitoring using wearable sensors provide a promising method to better understand fall risk by analyzing daily activity data from PwMS in real-world environments.
  • A new dataset was created from 38 PwMS, which includes walking data and assessments to explore how free-living walking bouts relate to fall risk; results show that longer walking bouts are more effective for distinguishing between fallers and non-fallers compared to shorter ones.
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Article Synopsis
  • Inertial measurement units (IMUs) allow for studying lower-limb movements outside of a lab setting, providing flexibility in research.
  • The authors developed an error-state Kalman filter to accurately estimate joint angles, stride length, and step width using data from seven wearable IMUs, incorporating a new method to correct joint axis measurements.
  • The technique was tested against optical motion capture with 20 subjects walking in various ways, showing joint angle differences under 5 degrees and stride measurements under 0.13 meters for most gaits, indicating strong potential for practical gait analysis.
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  • Wearable sensors are used to assess gait and balance impairment over long periods, but there's a need to determine the optimal duration for accurate data collection without causing excessive burden on patients.
  • Previous studies on sensor wear duration focused on various movement variables but often overlooked important measures like postural sway, highlighting the need for standardized methodologies.
  • A new three-level framework was proposed, suggesting that 2 to 3 days of monitoring may suffice for capturing variability, while longer durations could strengthen correlations with patient-reported outcomes, emphasizing the importance of observation frequency and measure variability.
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This editorial provides a concise overview of the use and importance of wearables in the emerging field of digital medicine [...

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Falls and mobility deficits are common in people with multiple sclerosis (PwMS) across all levels of clinical disability. However, functional mobility observed in supervised settings may not reflect daily life which may impact assessments of fall risk and impairment in the clinic. To investigate this further, we compared the utility of sensor-based performance metrics from sit-stand transitions during daily life and a structured task to inform fall risk and impairment in PwMS.

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Article Synopsis
  • Impaired sensory integration affects gait control and increases fall risk in individuals with multiple sclerosis (MS), leading researchers to explore the impact of non-specific axial loads, like weighted vests, on gait parameters.
  • A study with 12 MS participants and 11 healthy controls examined how wearing weighted vests affected their walking and turning performance, analyzing various gait parameters using wireless sensors.
  • Results showed significant differences in gait parameters between MS patients and controls, with both groups improving cadence and gait speed with added weight; particularly, the MS group benefited from increased vest weights, which improved stride length and reduced double support time.
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