Publications by authors named "Ryan Pike"
In order to better understand the spatial spread of bovine tuberculosis (bTB) in Wales, an All Wales Badgers Found Dead (AWBFD) survey was carried out from 2014-2016. For Wales, as a whole, there was a significant decrease (p < 0.001) in prevalence of bTB in badgers since a similar survey was carried out in 2005-2006, with a drop from 13.
View Article and Find Full Text PDFArticle Synopsis
- Developed a new method for creating 2,5-dialkyl-4,6,7-tricyanoindole derivatives using a base-catalyzed reaction.
- The process involves condensing two fumaronitrile molecules with one 1,3-diketone molecule.
- This reaction efficiently cleaves a specific carbon bond in the diketone and forms several new bonds, generating both aryl and pyrrole rings of the indole in a single step.
Extending on earlier work, trends in bovine tuberculosis (bTB) from 2003 to 2015 are described for the countries of the UK and the Republic of Ireland using standardised definitions and measures. Based on measures of animal and herd incidence, there remains a stable situation of extremely low prevalence in Scotland and the Low Risk Area of England, and a higher but ongoing reduction in prevalence in the Republic of Ireland. In Northern Ireland, there has been a rising bTB trend during 2010-2015, although not to levels experienced during 2002-2004.
View Article and Find Full Text PDFWe report the first example of a very general Cu-catalyzed cross-coupling of organoaluminum reagents with organohalides. The reactions proceed for the couplings of alkyl-, aryl-, and alkynylaluminum reagents with aryl and heteroaryl halides and vinyl bromides, affording the cross-coupled products in good to excellent yields. Both primary and secondary alkylaluminum reagents can be utilized as organometallic coupling partners.
View Article and Find Full Text PDF