Publications by authors named "Ryan P Chastain-Gross"

is an oral opportunistic pathogen. Sequenced laboratory strains display limited diversity in antigens that modulate host responses. Here, we present the genome sequence of A7A1-28, a strain possessing atypical fimbrillin and capsule types, with a single contig of 2,249,024 bp and a G+C content of 48.

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Porphyromonas gingivalis is associated with both oral and systemic diseases. Strain-specific P. gingivalis invasion phenotypes do not reliably predict disease presentation during in vivo studies.

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Article Synopsis
  • Porphyromonas gingivalis is linked to both oral health issues and broader systemic diseases.
  • Specific strains of this bacteria show different invasion traits that relate to how diseases manifest in infected lab animals.
  • The genome of the minimally invasive strain AJW4 has been sequenced, revealing a single DNA segment that is 2,372,492 base pairs long with a G+C content of 48.27%.
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Porphyromonas gingivalis is strongly associated with periodontitis. P. gingivalis strain trafficking and tissue homing differ widely, even among presumptive closely related strains, such as W83 and A7436.

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