Publications by authors named "Ryan Njeim"
Article Synopsis
- Patients with autoimmune diseases, particularly those with inflammatory bowel disease (IBD), face a higher risk of metabolic syndrome (MetS) and cardiovascular disease (CVD), yet research on this is limited.
- A retrospective study examining data from the National Inpatient Sample over five years found that while IBD patients had lower overall prevalence of MetS components compared to non-IBD patients, ulcerative colitis (UC) patients had a higher prevalence than those with Crohn's disease (CD).
- The study demonstrated that higher metabolic scores associated with MetS components were linked to increased risks of acute coronary syndrome and arrhythmias, with significant odds ratios indicating a strong correlation between MetS and heart failure in both IBD types.
β-thalassemias are genetic disorders causing an imbalance in hemoglobin production, leading to varying degrees of anemia, with two clinical phenotypes: transfusion-dependent thalassemia (TDT) and non-transfusion-dependent thalassemia (NTDT). Red blood cell transfusions and iron chelation therapy are the conventional treatment options for the management of β-thalassemia. Currently available conventional therapies in thalassemia have many challenges and limitations.
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