Publications by authors named "Ryan Leow"
Differentiation of the severity of rheumatic mitral stenosis using dimensionless index and its association with outcomes.
Int J Cardiol Cardiovasc Risk Prev
March 2025
Introduction: The severity of mitral stenosis (MS) is commonly assessed using mitral valve area (MVA) measured with transthoracic echocardiography (TTE). The dimensionless index (DI) of mitral valve (MV) was recently studied in degenerative MS. We evaluated DI MV in rheumatic MS and studied its relationship with clinical outcomes.
View Article and Find Full Text PDFYeo's index, the product of the mitral leaflet separation index and dimensionless index of mitral valve (MV), was recently described to accurately identify severe rheumatic mitral stenosis (MS). We assess the association between Yeo's index and clinical outcomes in patients with rheumatic MS. We studied 297 patients with rheumatic MS.
View Article and Find Full Text PDFArticle Synopsis
- Net atrioventricular compliance (C) impacts the accuracy of mitral valve area (MVA) assessment in patients with rheumatic mitral stenosis (MS).
- In a study with 244 patients, it was found that MVA measurements using different methods showed poor concordance with the most accurate assessment, TEE 3DMVA, particularly in those with abnormal C.
- The research indicated that patients with a 2D planimetry MVA of ≤1.5 cm and a pressure half-time (PHT) of ≤130 ms are likely to have abnormal C, making MVA by PHT an unreliable measure in these cases.
Article Synopsis
- - Yeo's index is a new metric for assessing the severity of rheumatic mitral valve stenosis (MS), based on mitral leaflet separation and dimensionless index comparisons, and its effectiveness was tested against TEE's 3D mitral valve area (MVA).
- - In a study with 111 patients, Yeo's index showed the strongest correlation (r = 0.775) with TEE 3DMVA, outperforming traditional echocardiographic methods like 2D planimetry, continuity equation (CE), and pressure half-time (PHT).
- - The study concluded that Yeo's index is a reliable tool for identifying severe MS and could be particularly effective when used alongside 2D
Article Synopsis
- Yeo's Index is a new measurement for determining the severity of rheumatic mitral stenosis (MS), based on mitral leaflet separation and a dimensionless index.
- In a study involving 237 patients, it was found that Yeo's index ≤ 0.26 cm had a high sensitivity (93%) and specificity (87.5%) for identifying severe MS, while a threshold of ≤ 0.15 cm was effective for very severe MS, with sensitivity and specificity values of 83.6% and 94.3%, respectively.
- The index's effectiveness was consistent across patients with isolated MS and those with mixed valve disease, and the presence of atrial fibrillation did not affect its accuracy.
Background: A mitral leaflet separation index (MLSI), measuring the anatomical separation of the mitral valve (MV) leaflet tips in diastole, was previously described as an accurate method of assessing mitral stenosis (MS). We propose a novel modification of the MLSI by including a hemodynamic assessment which we term Yeo's index that may improve its diagnostic performance.
Methods And Results: We retrospectively studied 174 patients with varying severity of MS without significant mitral regurgitation, aortic valve disease or ventricular septal defect.
Prognostic value of left atrial volume index in degenerative mitral stenosis.
Int J Cardiovasc Imaging
December 2022
Article Synopsis
- The study investigates the prognostic significance of left atrial volume index (LAVI) in patients with degenerative mitral stenosis (DMS), highlighting the correlation of LAVI with patient outcomes.
- Patients were divided into two groups based on LAVI size; those with enlarged LAVI had worse prognosis, higher left ventricular mass index, and more severe heart conditions compared to those with normal-sized LAVI.
- Findings indicate that an enlarged LAVI (greater than 34 ml/m2) is linked to increased mortality risk, making it a significant predictor of poor outcomes in DMS patients.
Background: Infective endocarditis (IE) confers significant mortality and morbidity in patients with underlying mitral stenosis (MS), with both diseased native valves and after valvular procedures.
Purpose: We examined the clinical and echocardiographic parameters in association with the development of IE on patients with significant MS.
Methods: A total of 478 consecutive patients with index echocardiographic diagnosis of significant mitral stenosis (mitral valve area <1.