Publications by authors named "Ryan Kingsley"

Article Synopsis
  • Alpha-1 adrenergic receptor (α1-AR) antagonists are drugs often used to treat benign prostatic hyperplasia and hypertension, but their potential link to cognitive impairment remains debated.
  • A systematic review was conducted to evaluate the association between these medications and cognitive dysfunction, analyzing 7 studies, primarily focusing on tamsulosin.
  • The findings suggested no strong causal relationship between α1-AR antagonists and cognitive issues, indicating these medications can be used without significant concern for affecting cognition.
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Purpose: Point-of-care ultrasound (POCUS) inclusion in medical education is increasing, and understanding of clinical educators' perceptions and use patterns is needed. The purpose of this research project was to explore current use, interest, knowledge, perceptions, and readiness to teach POCUS from the perspectives of clinical preceptors for physician assistant (PA) students.

Methods: A survey research study was completed on previously identified preceptors.

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Remdesivir use in COVID-19 is associated with cardiac conduction abnormalities from unclear mechanisms. A proposed mechanism is the bioaccumulation of the intermediate metabolite GS-441524 resulting in exogenous activation of cardiac adenosine A1 due to the structural similarity between adenosine and GS-441524. The prolonged half-life of GS-441524 can result in sustained activation of adenosine A1 receptors.

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