Publications by authors named "Ryan K Sisk"
Article Synopsis
- The study investigates whether polymorphisms in the anti-Müllerian hormone (AMH) promoter affect AMH levels in women with polycystic ovary syndrome (PCOS).
- A specific polymorphism, rs10406324, is linked to lower serum AMH levels, suggesting it influences AMH gene expression regulation in these women.
- The research included a large cohort of PCOS patients and additional control groups, using various genetic and laboratory methods to analyze the relationships between AMH promoter SNPs and AMH levels.
Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.
J Clin Endocrinol Metab
August 2014
Context: Polycystic ovary syndrome (PCOS) is a highly heritable complex trait. Parents of affected women have reproductive and metabolic phenotypes.
Objective: We tested the hypothesis that there are parental effects on the heritability of fasting dysglycemia in women with PCOS.