The Moderating Role of Context Processing in the Intergenerational Transmission of Posttraumatic Stress.

This pilot study aimed to understand the moderating role of context processing (i.e. encoding and memorizing) when mothers are confronted with threatening stimuli and undergo physiologic monitoring in order to understand a possible mechanism favoring intergenerational transmission of posttraumatic stress.

Brain Reactivity and Vulnerability to Social Feedback Following Acute Stress in Early Adolescence.

Introduction: Early adolescence is a time of high psychosocial stress exposure and high stress reactivity, associated with the development of mental disorders. Understanding how the brain reacts to acute and social stressors during this period might help us detect and protect those at risk.

Methods: We used functional magnetic resonance imaging to investigate acute social stress reactivity in non-clinical adolescents between ages 13 and 15 years (N = 61) with a range of depression scores (Beck Depression Inventory scores 0-32).

Mixed emotions to social situations: An fMRI investigation.

Background: Neuroscience research has generally studied emotions each taken in isolation. However, mixed emotional states (e.g.

Identifying Disease-Specific Neural Reactivity to Psychosocial Stress in Borderline Personality Disorder.

Background: Patients with borderline personality disorder (BPD) typically present emotion dysregulation (ED) when faced with adversity. However, it is argued that altered stress response may be more influenced by ED than BPD-specific traits. Here, we investigated this issue with functional magnetic resonance imaging using another ED condition as clinical control, i.

Interoceptive active inference and self-representation in social anxiety disorder (SAD): exploring the neurocognitive traits of the SAD self.

This article provides an interoceptive active inference (IAI) account of social anxiety disorder (SAD). Through a neurocognitive framework, we argue that the cognitive and behavioural profile of SAD is best conceived of as a form of maladaptive IAI produced by a negatively biased self-model that cannot reconcile inconsistent tendencies to approach and avoid social interaction. Anticipated future social interactions produce interoceptive prediction error (bodily states of arousal).

Temporal dynamics of amygdala response to emotion- and action-relevance.

It has been proposed that the human amygdala may not only encode the emotional value of sensory events, but more generally mediate the appraisal of their relevance for the individual's goals, including relevance for action or task-based needs. However, emotional and non-emotional/action-relevance might drive amygdala activity through distinct neural signals, and the relative timing of both kinds of responses remains undetermined. Here, we recorded intracranial event-related potentials from nine amygdalae of patients undergoing epilepsy surgery, while they performed variants of a Go/NoGo task with faces and abstract shapes, where emotion- and action-relevance were orthogonally manipulated.

Functional connectivity mapping of regions associated with self- and other-processing.

Neuroscience literature increasingly suggests a conceptual self composed of interacting neural regions, rather than independent local activations, yet such claims have yet to be investigated. We, thus, combined task-dependent meta-analytic connectivity modeling (MACM) with task-independent resting-state (RS) connectivity analysis to delineate the neural network of the self, across both states. Given psychological evidence implicating the self's interdependence on social information, we also delineated the neural network underlying conceptual other-processing.

The functional profile of the human amygdala in affective processing: insights from intracranial recordings.

The amygdala is suggested to serve as a key structure in the emotional brain, implicated in diverse affective processes. Still, the bulk of existing neuroscientific investigations of the amygdala relies on conventional neuroimaging techniques such as fMRI, which are very useful but subject to limitations. These limitations are particular to their temporal resolution, but also to their spatial precision at a very fine-grained level.

Degrees of separation: a quantitative neuroimaging meta-analysis investigating self-specificity and shared neural activation between self- and other-reflection.

In functional neuroimaging studies, self-specificity has been investigated by contrasting other-relevant processing against the self. Our meta-analysis investigates self-specificity with respect to degrees of self-relatedness (SR) of the other (i.e.