New diagnostic aids for melanoma.

Detection of melanoma at an early stage is crucial to improving survival rates in melanoma. Accurate diagnosis by current techniques including dermatoscopy remains difficult, and new tools are needed to improve our diagnostic abilities. This article discusses recent advances in diagnostic techniques including confocal scanning laser microscopy, MelaFind, SIAscopy, and noninvasive genomic detection, as well as other future possibilities to aid in diagnosing melanoma.

Possible role of hypercoagulability in calciphylaxis: review of the literature.

Background: The role of a hypercoagulable state in the pathogenesis of calciphylaxis has yet to be determined.

Objective: We sought to find evidence of an association between hypercoagulability and calciphylaxis.

Methods: We reviewed the primary literature for review articles, studies, and case reports that discussed or demonstrated a possible relationship between calciphylaxis and a hypercoagulable state.