Publications by authors named "Ryan J Cali"

Article Synopsis
  • The effects of repeated blast exposure (RBE) on the brain health of US Special Operations Forces (SOF) are not fully understood, and currently, there is no test to diagnose injury from such exposures.
  • A study involving 30 active-duty US SOF found that higher blast exposure correlates with changes in brain structure and cognitive performance, particularly affecting the rostral anterior cingulate cortex (rACC).
  • These findings indicate that increased blast exposure can lead to health-related issues and suggest that a comprehensive, network-based diagnostic method may be beneficial for identifying brain injuries in SOF personnel.
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In brain imaging research, it is becoming standard practice to remove the face from the individual's 3D structural MRI scan to ensure data privacy standards are met. Face removal - or 'defacing' - is being advocated for large, multi-site studies where data is transferred across geographically diverse sites. Several methods have been developed to limit the loss of important brain data by accurately and precisely removing non-brain facial tissue.

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Article Synopsis
  • United States Special Operations Forces (SOF) often experience explosive blasts during training and combat, which can affect their brain health.
  • The understanding of how repeated blast exposure impacts the brain is still lacking, and there is no existing diagnostic test for repeated blast brain injury (rBBI).
  • Developing a reliable test for rBBI could enhance SOF brain health, improve combat readiness, and enhance their overall quality of life.
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In brain imaging research, it is becoming standard practice to remove the face from the individual's 3D structural MRI scan to ensure data privacy standards are met. Face removal - or 'defacing' - is being advocated for large, multi-site studies where data is transferred across geographically diverse sites. Several methods have been developed to limit the loss of important brain data by accurately and precisely removing non-brain facial tissue.

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Emerging evidence suggests that repeated blast exposure (RBE) is associated with brain injury in military personnel. United States (U.S.

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Background: Hypertension-related illnesses are a leading cause of disability and death in the United States, where hypertension prevalence in adults is 46%, with only half of those afflicted having it under control. Due to the significant challenges in long-term efficacy and adverse effects associated with pharmacological interventions, there is an eminent need for complimentary approaches for treating hypertension. Although initial studies of the Mindfulness-Based Blood Pressure Reduction program (MB-BP) indicate that this novel 8-week intervention is effective at inducing lasting decreases in blood pressure, the neural correlates are unknown.

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Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder caused by mutation of the gene presenting with numerous colorectal adenomatous polyps and a near 100% risk of colon cancer. Preliminary research findings from our group indicate that FAP patients experience significant deficits across many cognitive domains. In the current study, fMRI brain metrics in a FAP population and matched controls were used to further the mechanistic understanding of reported cognitive deficits.

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Obesity is associated with significant comorbidities and financial costs. While behavioral interventions produce clinically meaningful weight loss, weight loss maintenance is challenging. The objective was to improve understanding of the neural and psychological mechanisms modified by mindfulness that may predict clinical outcomes.

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Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder caused by mutation of the APC gene presenting with numerous colorectal adenomatous polyps and a near 100% risk of colon cancer. Preliminary research findings from our group indicate that FAP patients experience significant deficits across many cognitive domains. In the current study, fMRI brain metrics in a FAP population and matched controls were used to further the mechanistic understanding of reported cognitive deficits.

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