Publications by authors named "Ryan Instrum"

Background: The aim of this study was to evaluate speech outcomes following surgical intervention for velopharyngeal dysfunction (VPD). Perceptual speech outcome data were subsequently analyzed in conjunction with patient factors such as congenital abnormalities, presence of cleft lip and/or palate, and age of repair. We hope to aid in the eventual creation of treatment algorithms for VPD, allowing practitioners to tailor surgical technique selection to patient factors.

View Article and Find Full Text PDF

Objectives/hypothesis: Nasopharyngeal swabs currently remain the gold standard for COVID-19 sample collection. A surge in testing volume has resulted in a large number of health care workers who are unfamiliar with nasal anatomy performing this test, which can lead to improper collection practices culminating in false-negative results and complications. Therefore, we aimed to assess the accuracy and educational potential of a realistic 3D-printed nasal swab simulator to expedite health care workers' skill acquisition.

View Article and Find Full Text PDF

Purpose of Chapter: This chapter discusses the recent progress made in understanding the pathophysiology, diagnosis, and treatment of benign paroxysmal positional vertigo (BPPV). Recent Findings: Recent evidence supports the canalolithiasis model as the pathophysiological mechanism and predominant subtype of BPPV. Scanning electron micrographs of extracted posterior semicircular canal contents show free-floating otoconia of utricular origin.

View Article and Find Full Text PDF
Benign paroxysmal positional vertigo.

Laryngoscope Investig Otolaryngol

February 2019

Objectives: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular end-organ disease. This article aims to summarize research findings and key discoveries of BPPV. The pathophysiology, diagnosis, nonsurgical, and surgical management are discussed.

View Article and Find Full Text PDF

Objective: To assess the efficacy and safety of two different intratympanic dexamethasone (IT Dex) injection protocols for intractable unilateral Ménière's disease.

Study Design: Prospective case series.

Setting: Tertiary neurotology clinic.

View Article and Find Full Text PDF

Objective: To review the quality of clinical practice guidelines (CPGs) from a wide range of health care topics and report any changes seen since 1992.

Study Design And Setting: A literature search in MEDLINE, EMBASE, Web of Science Core Collection, and BIOSIS was conducted in London, Ontario, Canada. Publications were screened to identify those assessing the quality of CPGs using the Appraisal of Guidelines, Research and Evaluation (AGREE) II instrument.

View Article and Find Full Text PDF