Publications by authors named "Ryan Hirsch"

Background And Aim: Atrophic gastritis (AG) and gastric intestinal metaplasia (GIM) are early changes in the stepwise progression to gastric adenocarcinoma. There is heterogeneity in international guidelines regarding the endoscopic diagnosis and surveillance of AG and GIM. This study aims to determine the prevalence of GIM in an Australian center and assess the approach of Australian endoscopists for these two conditions.

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Article Synopsis
  • The use of GLP-1 agonists like semaglutide is rising for weight loss and managing non-alcoholic steatohepatitis (NASH), but safety data for NASH cirrhotic patients is limited.
  • A documented case showed a patient with NASH-cirrhosis experienced liver decompensation after rapid weight loss on semaglutide, leading to the need for liver transplant waitlisting.
  • Following the cessation of semaglutide and nutritional support, the patient's condition improved, allowing her to be removed from the transplant list, emphasizing the importance of caution and further research in treating cirrhotic patients with these medications.
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Background: Dysplasia surveillance in inflammatory bowel disease (IBD) is often suboptimal and deviates from guidelines.

Aims: To assess dysplasia surveillance behaviours and adherence to guidelines amongst a large tertiary teaching health network with a specialised IBD unit to identify areas where dysplasia surveillance could be improved.

Methods: A retrospective audit of IBD surveillance colonoscopy practice over an 18-month period was performed using the Provation Endoscopy Database and the hospital's primary sclerosing cholangitis database.

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Background: Hepatocellular carcinoma (HCC) is responsible for 1% of deaths worldwide, and the incidence continues to increase. Despite surveillance programs, 70% of HCC patients are not suitable for curative options at diagnosis, and therefore, non-curative treatments are essential to modern clinical practice. There are many novel treatments, though their roles are not well defined.

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A 68 year old male presented to our Emergency Department with a one-day history of right sided abdominal pain, distention and vomiting on a background of no previous abdominal surgery. Abdominal CT demonstrated a high grade, closed loop small bowel obstruction involving the terminal segment of the ileum. Also of significance was alow-density appendiceal nodule.

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