(4-(Adamantan-1-yl)-1-(isopropyl)-1-imidazol-2-yl)methanol.

(4-(Adamantan-1-yl)-1-(isopropyl)-1-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps was 28%. The compound was identified and characterized by H and C{H} NMR, high-resolution mass spectroscopy, and elemental analysis.

Synthesis and Characterization of Bipyridyl-(Imidazole) Mn(II) Compounds and Their Evaluation as Potential Precatalysts for Water Oxidation.

Metalloenzymes make extensive use of manganese centers for oxidative catalysis, including water oxidation; the need to develop improved synthetic catalysts for these processes has long motivated the development of bioinspired manganese complexes. Herein, we report a series of bpy-(imidazole) (n = 1 or 2) (bpy = 2,2'-bipyridyl) ligands and their Mn complexes. Four Mn complexes are structurally characterized using single-crystal X-ray diffraction, revealing different tridentate and tetradentate ligand coordination modes.

Steric Effects on the Chelation of Mn and Zn by Hexadentate Polyimidazole Ligands: Modeling Metal Binding by Calprotectin Site 2.

Recently, there has been increasing interest in the design of ligands that bind Mn with high affinity and selectivity, but this remains a difficult challenge. It has been proposed that the cavity size of the binding pocket is a critical factor in most synthetic and biological examples of selective Mn binding. Here, we use a bioinspired approach adapted from the hexahistidine binding site of the manganese-sequestering protein calprotectin to systematically study the effect of cavity size on Mn and Zn binding.

A stable Cerberus tris(maloNHC) and its coinage metal complexes.

The first trisanionic Cerberus-type maloNHC has been generated and coordinated to two different coinage metals (Au(i) and Ag(i)). The resulting triszwitterionic metal complexes have been characterized by NMR spectroscopy, elemental analysis, and X-ray crystallography. The molecular structures of the new metal complexes reveal an average AuAu and AgAg separation of 20.

Gregariousness does not vary with geography, developmental stage, or group relatedness in feeding redheaded pine sawfly larvae.

Aggregations are widespread across the animal kingdom, yet the underlying proximate and ultimate causes are still largely unknown. An ideal system to investigate this simple, social behavior is the pine sawfly genus , which is experimentally tractable and exhibits interspecific variation in larval gregariousness. To assess intraspecific variation in this trait, we characterized aggregative tendency within a single widespread species, the redheaded pine sawfly ().