Publications by authors named "Ryan D Hoffman"

Article Synopsis
  • The study explores the use of the muscle-sparing thoracodorsal artery perforator (TDAP) flap for breast reconstruction when abdominal flaps are not an option, addressing challenges like volume limitations and risk of necrosis.
  • A total of 14 patients underwent surgically delayed TDAP flap reconstruction between April 2021 and August 2023, with data collected on flap dimensions, surgical timing, and complications.
  • Results showed improved vascular measurements post-delay and highlighted a low complication rate, suggesting that the delay phenomenon may enhance the effectiveness of TDAP flaps for breast reconstruction.
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Article Synopsis
  • - Autologous reconstruction makes up about 25% of breast reconstructions in the U.S., with the abdomen being the most common donor site; however, in this case, a 62-year-old woman needed an alternative due to complications from her previous implant-based reconstruction.
  • - The patient had significant capsular contracture and was not a candidate for the preferred deep inferior epigastric perforator flap due to her surgical history, so the thoracodorsal artery perforator (TDAP) flap was selected as a less invasive option.
  • - The study highlights the use of a surgically delayed TDAP flap as a reliable alternative for total autologous breast reconstruction, potentially avoiding more invasive procedures or the need
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Article Synopsis
  • The study aimed to compare the success rates of two limb salvage techniques: regenerative limb salvage (rLS) using dehydrated human chorion amnion membrane (dHACM) and traditional flap-based limb salvage (fLS).
  • Conducted over three years, the research involved patients with complex extremity wounds and measured outcomes such as reconstruction success, exposed structures persistence, closure time, and weight-bearing time.
  • Results indicated that both methods had similar success rates, with 85.7% for fLS and 80% for rLS, suggesting that rLS is a viable option for treating complex wounds.
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Article Synopsis
  • The study examines the enhancement of the superficial inferior epigastric artery (SIEA) flap for breast reconstruction by implementing a surgical delay to improve its reliability.
  • A total of 17 patients underwent either delayed SIEA or deep inferior epigastric (DIEP) reconstruction, with data collected on operative time, hospital stay, and complications.
  • Results showed that the SIEA diameter significantly increased after surgical delay, leading to low complication rates and suggesting that this method enhances the flap's reliability for reconstruction.
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  • Sarcopenia, a condition linked to poor surgical outcomes, was studied to see how it affects complications in patients undergoing lower extremity reconstruction and compared two assessment methods (traditional vs. novel "ellipse method").
  • A retrospective study of 50 patients showed that sarcopenia rates were higher using the ellipse method, with sarcopenic patients being older, more often female, and more diabetic.
  • The ellipse method proved to be more accurate in predicting complications and indicated that sarcopenic patients had a greater risk for postoperative issues, suggesting it's a useful tool for clinical evaluations.
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  • Incisional hernias are caused by poor healing of surgical cuts and differ from primary hernias; this study focuses on health disparities in their repair across the U.S.!
  • Analyzed data from 2012 to 2014 showed that approximately 89,258 procedures occurred annually, leading to $6.3 billion in hospital costs, with factors like age, race, and insurance status affecting outcomes.!
  • Findings revealed that nonelective repairs are linked to higher in-hospital mortality and longer hospital stays, particularly affecting older adults, women, and non-White patients, indicating a need for awareness among healthcare providers regarding these disparities.!
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Article Synopsis
  • Incisional hernias (IH) affect about 400,000 new patients annually, and if not repaired, they can lead to serious health complications and even death; however, health disparities related to IH have not been thoroughly studied.
  • A study using inpatient admission data from 2012-2014 revealed that 38.5% of IH cases were urgent or emergent, with higher rates in patients over 65, females, and self-paying individuals, alongside significant racial disparities.
  • The findings indicate that older, female, non-white, and uninsured populations are at greater risk for needing urgent care for IH complications, highlighting the need for targeted strategies to address these healthcare disparities.*
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Article Synopsis
  • - The study aimed to assess the prevalence of anatomical variations in the radial artery that could impact the harvesting of the radial forearm flap (RFF) for reconstructive surgery, addressing the limitations of the Allen test.
  • - A systematic review was conducted, analyzing 18 angiogram studies with over 18,000 patients, which found that while accessory branches were rare (0.5%), several other anatomical variations had notable prevalence rates, such as tortuosity (4.3%) and abnormal origin (5.6%).
  • - The findings emphasize the importance of comprehensive screening for anatomical variations before RFF harvest, as these variations could potentially lead to complications, even though the risk of flap loss from accessory branches is low.
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Hypoxia is a pervasive stressor in aquatic environments, and both phenotypic plasticity and evolutionary adaptation could shape the ability to cope with hypoxia. We investigated evolved variation in hypoxia tolerance and the hypoxia acclimation response across fundulid killifishes that naturally experience different patterns of hypoxia exposure. We compared resting O consumption rate ( ), and various indices of hypoxia tolerance [critical O tension (), regulation index (RI), O tension ( ) at loss of equilibrium () and time to LOE () at 0.

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