peritonitis in a patient on hemodialysis for end-stage renal disease secondary to lupus nephritis-a case report.

Key Clinical Message: Patients with a recent history of peritoneal dialysis catheter removal in the setting of immunosuppression should be monitored for rare bacterial peritonitis. This infection should be managed with ampicillin and gentamicin.

Abstract: There are scattered reports to date of patients with peritonitis caused by .

Inhibition of the oncogenic fusion protein EWS-FLI1 causes G-M cell cycle arrest and enhanced vincristine sensitivity in Ewing's sarcoma.

Ewing's sarcoma (ES) is a rare and highly malignant cancer that grows in the bones or surrounding tissues mostly affecting adolescents and young adults. A chimeric fusion between the RNA binding protein EWS and the ETS family transcription factor FLI1 (EWS-FLI1), which is generated from a chromosomal translocation, is implicated in driving most ES cases by modulation of transcription and alternative splicing. The small-molecule YK-4-279 inhibits EWS-FLI1 function and induces apoptosis in ES cells.