A Combinatorial Vaccine Containing Inactivated Bacterin and Subunits Provides Protection Against Infection in Mice and Pigs.

(APP) is the etiological agent of porcine contagious pleuropneumonia (PCP) that causes great economic losses in the swine industry. Currently, vaccination is still a commonly used strategy for the prevention of the disease. Commercially available vaccines of this disease, including inactivated bacterins and subunit vaccines, have clinical limitations such as side effects and low cross-protection.