Publications by authors named "Ruyu Ma"

Non-alcoholic fatty liver disease (NAFLD) represents a complex complication of type 2 diabetes mellitus (T2DM). Oxymatrine (OMT) is an alkaloid extracted from Sophora flavescens with broad pharmacological effects. However, there is currently a lack of research on OMT in the field of NAFLD.

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Objective: To investigate the protective effects and possible mechanisms of ferulic acid on diabetic nephropathy by observing the effects of ferulic acid on the level of inflammation and autophagy in glomerular mesangial cells induced by high glucose.

Methods: SV40 MES 13 cells were cultured and randomly divided into the following groups: normal group (Control, 5.6 mmol/L glucose), mannitol group (Man, 30 mmol/L mannitol), high glucose group (HG, 30 mmol/L glucose), ferulic acid group (FA, 30 mmol/L glucose + 12.

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Diabetic nephropathy (DN) is one of the most serious microvascular complications following diabetes mellitus (DM). Ferulic acid (FA), a phenolic acid widely found in plants, has multiple pharmacological effects such as anti-oxidation, anti-inflammation and anti-tumor. However, the current research on FA in the field of DN is insufficient.

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Moire profilometry (MP) is one of the three-dimensional (3D) topography measurement methods of structured light, which has the advantages of single frame reconstruction, high speed, no contact and high precision, and is suitable for dynamic measurement scenes. In this article, the digital MP is applied to the wheel tread measurement, the virtual grating is generated by computer to project to the object surface, the moire fringe pattern of the object is obtained by filtering, and finally the continuous phase pattern is obtained by phase unwrapping. The 3D shape reconstruction of the wheel tread is realized, and a new method of wheel tread detection is provided.

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Interferometric fiber optic gyroscopes are widely used in spacecraft, navigation, and autopilot and missile systems due to their high accuracy and fast speed. However, the dynamic measurement range is generally limited to a small value. In this paper, an angular velocity measurement system based on a dual-comb Sagnac interferometer is proposed.

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Diabetic nephropathy (DN) is one of the complex and severe complications of diabetes mellitus (DM). Icariin (ICA) is a flavonoid extracted from the leaves and stems of Herba epimedii with a wide range of pharmacological effects, such as anti-osteoporosis, anti-fibrosis, anti-aging, anti-inflammation and antioxidation. The purpose of our study was to explore the renal protective effect of ICA on DN in mice and its possible mechanisms.

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Hydroxypropyl methylcellulose (HPMC) is a hydrophilic retarding-release polymer with the limited application in hot melt extrusion (HME) due to its high glass transition temperature (T 181-191°C) and melt viscosity. The aim of this study is to develop hot melt extruded matrices using hydroxypropyl cellulose (HPC) and felodipine (FLDP) with HPMC for controlled release and explore the relations of their specialty, processability, and structure with the product properties. Results showed that FLDP/HPC/HPMC can be extruded at 160°C with torques not more than 0.

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Parity-time (PT) symmetric structures present the unidirectional invisibility at the spontaneous PT-symmetry breaking point. In this paper, we propose a PT-symmetric circuit consisting of a resistor and a microwave tunnel diode (TD) which represent the attenuation and amplification, respectively. Based on the scattering matrix method, the circuit can exhibit an ideal unidirectional performance at the spontaneous PT-symmetry breaking point by tuning the transmission lines between the lumped elements.

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Fano resonance presents an asymmetric line shape formed by an interference of a continuum coupled with a discrete autoionized state. In this paper, we show several simple circuits for Fano resonances from the stable-input impedance mechanism, where the elements consisting of inductors and capacitors are formulated for various resonant modes, and the resistor represents the damping of the oscillators. By tuning the pole-zero of the input impedance, a simple circuit with only three passive components e.

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In order to help a surgeon to determine a proper canal filing cutting path in a hip replacement operation conveniently, this paper presents a kind of probe with combined structure. Firstly, the doctor can use this kind of combined probe to choose canal filing cutting path. Then, the doctor can use computer to guide the surgeon to file femoral cavity along the selected canal filing cutting path.

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In a hip replacement case when a standard hip stem is chosen, it is rough to select hip stems before operation, thus some stand-up standard hip stems should be prepared. The operation time is usually prolonged. In order to solve this problem, this paper presents a method to automatically select optimal standard hip stems by computers.

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A novel method for the design of hip joint prostheses based on X-ray films is introduced. Only arcs and straight-lines form figures of hip joint prostheses. Because geometrical tolerances of manufacturing hip joint prostheses matching section are usually not strict, hip joint prostheses can be manufactured without CNC machine tool.

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