Associations of plasma biomarkers with cerebral perfusion and structure in Alzheimer's disease.

Plasma biomarkers have great potential in the screening, diagnosis, and monitoring of Alzheimer's disease (AD). However, findings on their associations with cerebral perfusion and structural changes are inconclusive. We examined both cross-sectional and longitudinal associations between plasma biomarkers and cerebral blood flow (CBF), gray matter (GM) volume, and white matter (WM) integrity.

Primary adenoid cystic carcinoma of the rib with metastases: A rare case report and literature review.

Adenoid cystic carcinoma (ACC) is a rare and aggressive malignant tumour predominantly found in the salivary glands but can also occur elsewhere. Primary ACC in the bones is particularly rare, with most reports focusing on cases of ACC in the maxilla and mandible. This report presents a case of ACC in a 47-year-old man with a primary origin in the right rib region, a previously unreported location.

A neuropsychological profile and its correlation with neuroimaging markers in patients with subcortical ischaemic vascular dementia.

Objectives: Cognitive and neuroimaging assessments are still the main clinical practice methods for screening and diagnosing vascular dementia (VaD) patients. This study aimed to establish the neuropsychological characteristics of mild-to-moderate subcortical ischaemic vascular dementia (SIVD) patients, find an optimal cognitive marker for differentiating them from Alzheimer's disease (AD) patients, and explore the correlation between cognitive function and total small vessel disease (SVD) burden.

Methods: SIVD (n = 60) and AD (n = 30) patients and cognitively unimpaired healthy controls (HCs; n = 30) were recruited from our longitudinal MRI AD and SIVD study (ChiCTR1900027943) and received a comprehensive neuropsychological assessment and a multimodal MRI scan.

Fe Dimers for Non-Polar Diatomic O Electroreduction.

Non-polar diatomic molecule activation is of great significance for catalysis. Despite the high atomic efficiency, the catalytic performance of single-atom catalysts is limited by insufficient receiving sites for diatomic molecule adsorption. Here, Fe dimers were successfully synthesized through precisely regulating the metal loading on metal-organic frameworks.

Selective Electrochemical Reduction of Nitrogen to Ammonia by Adjusting the Three-Phase Interface.

The electrochemical nitrogen reduction reaction (NRR) provides a sustainable and alternative avenue to the Haber-Bosch process for ammonia (NH) synthesis. Despite the great efforts made on catalysts and electrolytes, unfortunately, current NRR suffers from low selectivity due to the overwhelming competition with the hydrogen evolution reaction (HER). Here, we present an adjusted three-phase interface to enhance nitrogen (N) coverage on a catalyst surface and achieve a record-high Faradic efficiency (FE) up to 97% in aqueous solution.