Publications by authors named "Ruxandra Jurac"
Speckle tracking-echocardiography (STE) is a novel non-invasive imaging tool capable of quantifying myocardial deformation, and thus holds promise in detecting early subclinical myocardial injury. This study aimed to evaluate the correlation of STE with traditional biomarkers in predicting anthracycline-induced cardiotoxicity in the context of varying dosages and treatment protocols in pediatric hemato-oncology patients. We conducted a retrospective study involving pediatric hemato-oncology patients undergoing anthracycline-based chemotherapy.
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- Pediatric patients receiving anthracycline therapy for cancer are at risk for heart damage, with the study investigating how cancer type and treatment impact cardiac function.
- Advanced echocardiographic techniques like STE, GLS, and MPI may reveal early signs of heart issues that traditional methods miss.
- Results showed significant differences in heart function measurements between patients and controls, indicating poorer cardiac health in patients, with the combination of GLS, SMOD, and MPI being particularly effective in predicting cardiotoxicity risk.
Background: The recent emergence of Clostridium difficile infections has included this condition among top nosocomial infections, due to its incidence, complications and important fatality, as well as to significant economic costs.
Methods: A prospective surveillance study of Clostridium difficile enterocolitis cases was performed in "Victor Babeş" Infectious Diseases Hospital in Timişoara (Romania) between 01.01.