Publications by authors named "Ruwei Wei"
The shortwave infrared (SWIR) region is an ideal spectral window for next-generation bioimaging to harness improved penetration and reduced phototoxicity. SWIR spectral activity may also be accessed via supramolecular dye aggregation. Unfortunately, development of dye aggregation remains challenging.
View Article and Find Full Text PDFFluorophores absorbing/emitting in the deep near-infrared (deep NIR) spectral region, that is, 800 nm and beyond, hold great promise for in vivo bioimaging, diagnosis, and phototherapy due to deeper tissue penetration. The bottleneck is the lack of bright, stable, and readily synthesized deep NIR fluorophores. Here, it is reported that the albumin-chaperon strategy is a viable one-for-all strategy to address these difficulties.
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- The shortwave infrared (SWIR) region above 1200 nm is ideal for medical applications due to its deep tissue penetration and broad uses in diagnosis, therapy, and surgery.
- A new type of fluorochromic scaffold, a tetra-benzannulated xanthenoid, shows strong absorption and emission properties at 1204/1290 nm, with exceptional molar absorptivity and high transparency in visible light ranges.
- The novel fluorochrome demonstrates resistance to photobleaching and symmetry breaking, making it suitable for advanced imaging techniques, including high-contrast imaging of the hepatobiliary system and multi-channel imaging of other organs.
Near-infrared (NIR) fluorophores absorbing maximally in the region beyond 800 nm, i.e., deep-NIR spectral region, are actively sought for biomedical applications.
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